Chinese Journal of Integrative Medicine

, Volume 21, Issue 4, pp 307–311 | Cite as

Effect of Zhubin (KI9) acupuncture in reducing alcohol craving in patients with alcohol dependence: A randomized placebo-controlled trial

  • Jin-Seong Lee
  • Sung-Gon KimEmail author
  • Taek-Geun Jung
  • Woo Young Jung
  • Seong-Yeon Kim
Acupuncture Research



To examine the effect of acupuncture on Zhubin (KI9) in reducing alcohol craving in alcohol-dependent patients.


Twenty male alcohol-dependent patients were randomly assigned to two groups, a treatment group (10 cases, age 43.0±6.8 years) and a placebo group (10 cases, age 44.5±7.9 years). The treatment group was treated with real needle acupuncture on Zhubin (KI9) twice a week for 4 weeks, and the control group was treated with placebo needle acupuncture. Both groups were given acupuncture treatment using Park Sham Device (PSD). Alcohol craving was measured by the Visual Analogue Scale (VAS) before treatment to establish a baseline, and after 1, 2, and 4 weeks of treatment. Repeated measures ANOVA was used to determine the main and interaction effects of time and on the outcome measure (VAS).


There was a significant effect of time on VAS score (df=3, F=13.3, P<0.01). Main effect of group on VAS score was significant (df=1, F=10.9, P<0.01) and the time×group interaction was also significant (df=3, F=4.7, P<0.01).


Real-needle acupuncture therapy on Zhubin (KI9) showed effectiveness in reducing alcohol craving. These results strongly suggest the usefulness of acupuncture therapy on Zhubin (KI9) in preventing a relapse in alcohol dependent patients.


alcohol craving alcohol dependence acupuncture Zhubin (KI9) 


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Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Jin-Seong Lee
    • 1
  • Sung-Gon Kim
    • 1
    • 2
    Email author
  • Taek-Geun Jung
    • 3
  • Woo Young Jung
    • 1
  • Seong-Yeon Kim
    • 4
  1. 1.Department of PsychiatryPusan National University Yangsan HospitalYangsan, GyeongnamSouth Korea
  2. 2.Biomedical Research InstitutePusan National University HospitalPusanSouth Korea
  3. 3.Jang-Cheon Korean Medicine ClinicPusanSouth Korea
  4. 4.Division of Management Information Science (S-YK)Dong-A UniversityPusanSouth Korea

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