A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome
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To explore the regulative efficacy of Pu’er tea (普洱茶) extract on metabolic syndrome.
Ninety patients with metabolic syndrome were randomly divided into two groups, the intervention group administered with Pu’er tea extract, and the placebo group with placebo capsules. After 3 months’ treatment, body mass index, waist hip ratio, blood lipids, blood sugar, immune and inflammatory index, and oxidation index of the patients with metabolic syndrome were tested and analyzed.
In the intervention group, the body mass index, waist-hip ratio, fasting and 2 h postprandial blood glucose, serum total cholesterol, triglycerides, low density lipoprotein and apolipoprotein B-100 all decreased in the patients with metabolic syndrome, and also the high-density lipoprotein level increased and apolipoprotein A-1 showed the tendency to increase. Serum C-reactive protein, tumor necrosis factor-α, and interleukin-6 were decreased in the intervention group. Interleukin-10 level was increased, MDA was decreased and superoxide dismutase was increased. Compared with before treatment and the placebo group, there were significant differences (P<0.05, P<0.01).
Pu’er tea demonstrated excellent potential in improving central obesity, adjusting blood lipid, lowering blood sugar, regulating immunity and resisting oxidation. It can adjust the metabolic syndrome of different clinical phenotypes to different degrees, and is ideally fit for early prevention of metabolic syndrome.
Keywordstea metabolic syndrome randomized controlled clinical study
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- 1.Wang PS, Liang MZ. Foretime and now of Pu’er tea. Tropical Agricultural Sci Technol (Chin) 2001;24(4):23–27.Google Scholar
- 2.Metabolic Syndrome Study Group of Diabetes Branch of Chinese Medical Association. Recommendations on the metabolic syndrome of Diabetes Branch of Chinese Medical Association. Chin J Diabetes (Chin) 2004;12:156–160.Google Scholar
- 5.Xiao YX. Recognition and therapeutic thoughts on metabolism syndrome. Chin J Basic Med Tradit Chin Med (Chin) 2007;13:538–539.Google Scholar
- 6.Li XJ, Liu ZL. Discussion on treatment of metabolism syndrome from spleen. Guiding J Tradit Chin Med Pharmacol (Chin) 2006;12(4): 9–10.Google Scholar
- 7.Yuan HB, Zhong J, Yi J, Zhao Y, Cao J. Tea extract on diet-induced obese rats lipogenic gene expression. Acta Nutrimenta Sin (Chin) 2009;31:167–171.Google Scholar
- 8.Jiang XF, Shao WF, Hou Y. Study on the function of preventing the hyperlipidemia lipid level and the antioxidant of the Pu’er tea. J Yunnan Agricultural Univ (Chin) 2009;24:705–711.Google Scholar
- 9.Zhou BX, Kong LB, Chen JX. Study on extraction of Pu’er tea polysaccharides and hypoglycemic. Chin Agricultural Sci Bull (Chin) 2009;25(15):55–59.Google Scholar
- 11.Cardoso-Saldaña G, Juárez-Rojas JG, Zamora-González J, Raygoza-Pérez M, Martinez-Alvarado R, Posadas-Sánchez R, et al C-reactive protein levels and their relationship with metabolic syndrome and insulin resistance in Mexican adolescents. J Pediatr Endocrinol Metab 2007;20:797–805.PubMedCrossRefGoogle Scholar
- 16.Yang AF, Liu MY, Wang CQ, Ding HY, Xie XL, Xu YM, et al. Metabolic syndrome patients with oxidation — index changes of platelet aggregation. J Cardiovas Pulmonary Dis (Chin) 2004;23:228–230.Google Scholar