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Chinese Journal of Integrative Medicine

, Volume 17, Issue 7, pp 492–498 | Cite as

A randomized double-blind placebo-controlled study of Pu’er tea (普洱茶) extract on the regulation of metabolic syndrome

  • Song-ling Chu (褚松龄)
  • Hong Fu (富 宏)
  • Jin-xia Yang (杨金霞)
  • Geng-xin Liu (刘庚信)
  • Pan Dou (窦 攀)
  • Liang Zhang (张 良)
  • Peng-fei Tu (屠鹏飞)
  • Xue-mei Wang (王学美)
Original Article

Abstract

Objective

To explore the regulative efficacy of Pu’er tea (普洱茶) extract on metabolic syndrome.

Methods

Ninety patients with metabolic syndrome were randomly divided into two groups, the intervention group administered with Pu’er tea extract, and the placebo group with placebo capsules. After 3 months’ treatment, body mass index, waist hip ratio, blood lipids, blood sugar, immune and inflammatory index, and oxidation index of the patients with metabolic syndrome were tested and analyzed.

Results

In the intervention group, the body mass index, waist-hip ratio, fasting and 2 h postprandial blood glucose, serum total cholesterol, triglycerides, low density lipoprotein and apolipoprotein B-100 all decreased in the patients with metabolic syndrome, and also the high-density lipoprotein level increased and apolipoprotein A-1 showed the tendency to increase. Serum C-reactive protein, tumor necrosis factor-α, and interleukin-6 were decreased in the intervention group. Interleukin-10 level was increased, MDA was decreased and superoxide dismutase was increased. Compared with before treatment and the placebo group, there were significant differences (P<0.05, P<0.01).

Conclusions

Pu’er tea demonstrated excellent potential in improving central obesity, adjusting blood lipid, lowering blood sugar, regulating immunity and resisting oxidation. It can adjust the metabolic syndrome of different clinical phenotypes to different degrees, and is ideally fit for early prevention of metabolic syndrome.

Keywords

tea metabolic syndrome randomized controlled clinical study 

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Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Song-ling Chu (褚松龄)
    • 1
  • Hong Fu (富 宏)
    • 1
  • Jin-xia Yang (杨金霞)
    • 1
  • Geng-xin Liu (刘庚信)
    • 1
  • Pan Dou (窦 攀)
    • 1
  • Liang Zhang (张 良)
    • 2
  • Peng-fei Tu (屠鹏飞)
    • 2
  • Xue-mei Wang (王学美)
    • 1
  1. 1.Integration of Chinese and Western Medicine Laboratory of the First Hospital, Graduate School of Integration of Chinese and Western MedicineBeijing Medical UniversityBeijingChina
  2. 2.State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical SciencesPeking UniversityBeijingChina

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