Chinese Journal of Integrative Medicine

, Volume 16, Issue 3, pp 216–221 | Cite as

Effect of traditional and integrative regimens on quality of life and early renal impairment in elderly patients with isolated systolic hypertension

  • Hao Li (李 浩)
  • Long-tao Liu (刘龙涛)
  • Wen-ming Zhao (赵文明)
  • Jian-gang Liu (刘剑刚)
  • Ming-jiang Yao (姚明江)
  • Yong-xiang Han (韩永祥)
  • Yan-peng Shen (沈雁朋)
  • Xing-dong Liu (刘兴东)
  • Li Liu (刘 丽)
  • Xue-mei Wang (王雪梅)
  • Lin-lin Cai (蔡琳琳)
  • Jie Guan (官 杰)
Original Article

Abstract

Objective

To observe the effect of Chinese medical regimen and integrative medical regimen on quality of life and early renal impairment in elderly patients with isolated systolic hypertension (EISH).

Methods

A multi-center, randomized, double-blinded controlled trail was adopted. A total of 270 cases of EISH were randomly divided into 3 groups: Chinese medicine group (CM), combination group and Western medicine group (WM). The course of treatment was 4 weeks. The clinical blood pressure, integral of quality of life (SF-36 scale), immunoglubin G (IgG), microalbumin (mALB), β2-microglobulin (β2-MG), transferrin (TRF) and N-acetyl-β′-D-glucosa-minidase (NAG) in urine were determined before and after the treatment.

Results

After treatment, systolic blood pressure depressed significantly in each group (P<0.05), and the combination group was superior to CM or WM group in depressing SBP (P<0.05); in each group, integral of quality of life improved in different degree, and combination group was superior to WM group in all 8 dimensions (P<0.05). The level of mALB and β2-MG in urine decreased in all groups (P<0.05), and the combination group was superior to CM group or WM group in decreasing mALB (P<0.05).

Conclusions

Chinese medical regimen has affirmative effect in treating EISH patients, and could lower the systolic blood pressure, improve quality of life and early renal impairment of the patients, and integrative medical regimen has superiority on account of cooperation, and deserves further study.

Keywords

hypertension elderly Chinese medicine integrative medicine quality of life early renal impairment 

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Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Hao Li (李 浩)
    • 1
  • Long-tao Liu (刘龙涛)
    • 1
  • Wen-ming Zhao (赵文明)
    • 1
  • Jian-gang Liu (刘剑刚)
    • 1
  • Ming-jiang Yao (姚明江)
    • 1
  • Yong-xiang Han (韩永祥)
    • 2
  • Yan-peng Shen (沈雁朋)
    • 2
  • Xing-dong Liu (刘兴东)
    • 3
  • Li Liu (刘 丽)
    • 1
  • Xue-mei Wang (王雪梅)
    • 1
  • Lin-lin Cai (蔡琳琳)
    • 1
  • Jie Guan (官 杰)
    • 1
  1. 1.Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijingChina
  2. 2.Traditional Chinese Medicine Hospital of Yanqing CountyBeijingChina
  3. 3.Community Health Service Centers of Yanqing CountyBeijingChina

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