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Chinese Journal of Integrative Medicine

, Volume 16, Issue 1, pp 23–27 | Cite as

Treatment of non-alcoholic fatty liver disease by Qianggan Capsule (强肝胶囊)

  • Li Li (李 笠)
  • Xiao-jin Zhang (张小晋)Email author
  • Yu Lan (蓝 宇)
  • Le Xu (许 乐)
  • Xue-zhi Zhang (张学智)
  • Hua-hong Wang (王化虹)
Original Article

Abstract

Objective

To observe the therapeutic effect and safety of Qianggan Capsule (强肝胶囊, QGC) in treating non-alcoholic fatty liver disease (NAFLD), using polyene phosphatidylcholine capsule (PPC) as a reference.

Methods

Eighty-eight patients with NAFLD were randomly assigned to two groups, 45 in the treatment group treated with QGC and 43 in the control group treated with PPC. The course of treatment lasted for 6 months. Changes in liver function, blood lipids, and iconographic indexes before and after treatment were observed, and clinical efficacy was evaluated.

Results

In the treatment group, alanine aminotransferase (ALT) was lowered significantly from 56.02±32.59 IU/L before treatment to 38.27±22.68 IU/L after treatment, and CT liver/spleen ratio significantly increased from 0.69±0.18 to 0.91±0.25, showing statistical significance (P<0.05); in contrast, the corresponding changes of the two indexes in the control group were 56.56±26.33 IU/L to 49.67±26.22 IU/L, and 0.66±0.20 to 0.75±0.24, respectively, the pre-post treatment difference showing insignificant difference (P>0.05). No severe adverse reactions occurred during the whole treatment course.

Conclusion

QGC is an effective and safe remedy for the treatment of NAFLD.

Keywords

non-alcoholic fatty liver disease Chinese medicinal therapy Qianggan Capsule polyene phosphatidylcholine capsule 

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Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer Berlin Heidelberg 2010

Authors and Affiliations

  • Li Li (李 笠)
    • 1
  • Xiao-jin Zhang (张小晋)
    • 1
    Email author
  • Yu Lan (蓝 宇)
    • 1
  • Le Xu (许 乐)
    • 2
  • Xue-zhi Zhang (张学智)
    • 3
  • Hua-hong Wang (王化虹)
    • 3
  1. 1.Gastroenterology DepartmentBeijing Jishuitan HospitalBeijingChina
  2. 2.Beijing HospitalBeijingChina
  3. 3.The First Hospital Affiliated to Peking UniversityBeijingChina

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