Chinese Journal of Integrative Medicine

, Volume 14, Issue 2, pp 107–110

Effect of Shengmai Injection (生脉注射液) on cardiac function and inflammatory reaction in patients with acute coronary syndrome

  • Ya-chen Zhang (张亚臣)
  • Rui-ming Chen (陈瑞明)
  • Bao-jing Lu (吕宝经)
  • Ye-zhi Rong (荣烨之)
Original Article



To confirm the effect of Shengmai Injection (生脉注射液, SMI) in improving cardiac function in patients with acute coronary syndrome (ACS) and to explore its influence on inflammatory reaction in patients.


Ninety ACS patients were randomized into two groups, the control group treated with conventional therapy and the SMI group treated with SMI. The patients’ cardiac function was noted and the content of high sensitive C-reactive protein (hs-CRP) in venous blood was measured before treatment and 1 week and 3 weeks after treatment, so as to observe and compare their changes between the two groups.


The cardiac output, stroke volume and ejection fraction in the SMI group after 3 weeks of treatment were all higher than those in the control group (P<0.05). The serum content of hs-CRP was reduced in both groups (P<0.05), but the reduction in the SMI group was more significant than that in the control group (P<0.05).


SMI could improve the cardiac function and further inhibit the inflammatory reaction in patients with ACS.

Key words

Shengmai Injection acute coronary syndrome C-reactive protein inflammatory reaction cardiac function 


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Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag GmbH 2008

Authors and Affiliations

  • Ya-chen Zhang (张亚臣)
    • 1
  • Rui-ming Chen (陈瑞明)
    • 2
  • Bao-jing Lu (吕宝经)
    • 1
  • Ye-zhi Rong (荣烨之)
    • 1
  1. 1.Department of Internal CardiologyXinhua Hospital Affiliated to Shanghai Jiaotong Medical University School of MedicineShanghaiChina
  2. 2.Department of LaboratoryRuijin Hospital, Shanghai Jiaotong University School of MedicineShanghaiChina

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