Journal of Thermal Science

, Volume 21, Issue 3, pp 262–268 | Cite as

Particle image velocimetry experimental and computational investigation of a blood pump

  • Xiaochen Yang
  • Xingmin Gui
  • Hui Huang
  • Yongbin Shen
  • Ziwen Yu
  • Yan Zhang


Blood pumps have been adopted to treat heart failure over the past decades. A novel blood pump adopting the rotor with splitter blades and tandem cascade stator was developed recently. A particle image velocimetry (PIV) experiment was carried out to verify the design of the blood pump based on computational fluid dynamics (CFD) and further analyze the flow properties in the rotor and stator. The original sized pump model with an acrylic housing and an experiment loop were constructed to perform the optical measurement. The PIV testing was carried out at the rotational speed of 6952±50 r/min with the flow rate of 3.1 l/min and at 8186±50 r/min with 3.5 l/min, respectively. The velocity and the Reynolds shear stress distributions were investigated by PIV and CFD, and the comparisons between them will be helpful for the future blood pump design.


Blood pump Particle image velocimetry Computational fluid dynamics 


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  1. [1]
    Zhang, Y., Xue, S., Gui, X. M., et al., A Novel Integrated Rotor of Axial Blood Flow Pump Designed with Computational Fluid Dynamics, Artificial Organs, Vol.31, No.7, pp.580–585, (2007).CrossRefGoogle Scholar
  2. [2]
    Zhang, Y., Zhan, Z., Gui, X. M., et al., Design Optimization of an Axial Blood Pump with Computational Fluid Dynamics, ASAIO Journal, Vol.54, No.2, pp.150–155, (2008).CrossRefGoogle Scholar
  3. [3]
    Yang, X. C., Zhang, Y., Gui, X. M., and Hu, S. S., Computational Fluid Dynamics-Based Hydraulic and Hemolytic Analyses of a Novel Left Ventricular Assist Blood Pump, Artificial Organs, Vol.35, No.10, pp.948–955, (2011).CrossRefGoogle Scholar
  4. [4]
    Yang, X. C., Zhang, Y., Gui, X. M., and Hu, S. S., Computational Fluid Dynamics Analyses of a Micro Pediatric Ventricular Assist Blood Pump, ASME Paper AJK2011-06063, Hamamatsu, Japan, (2011).Google Scholar
  5. [5]
    Heuser, G., and Opitz, R., A Couette Viscometer for Short Time Shearing in Blood, Biorheology, Vol.17, No.1–2, pp.17–24, (1980).Google Scholar
  6. [6]
    Giersiepen, M., Wurzinger, L. J., Opitz, R., and Reul, H., Estimated of Shear Stress-Related Blood Damage in Heart Valve Prostheses-in Vitro Comparison of 25 Aortic Valves, International Journal of Artificial Organs, Vol.13, No.5, pp.300–306, (1990).Google Scholar
  7. [7]
    Burgreen, G. W., Antaki, J. F., Wu, Z. J., and Holmes, A. J., Computational Fluid Dynamics as a Development Tool for Rotary Blood Pumps, Artificial Organs, Vol.25, No.5, pp.336–340, (2001).CrossRefGoogle Scholar
  8. [8]
    Mitoh, A., Yano, T., Sekine, K., et al., Computational Fluid Dynamics Analysis of an Intra-Cardiac Axial Flow Pump, Artificial Organs, Vol.27, No.1, pp.34–40, (2003).CrossRefGoogle Scholar
  9. [9]
    Hariharan, P., Giarra, M., Reddy, V., et al., Multilaboratory Particle Image Velocimetry Analysis of the FDA Benchmark Nozzle Model to Support Validation of Computational Fluid Dynamics Simulations, ASME Journal of Biomechanical Engineering, Vol.133, No.4, pp.041002, (2011).CrossRefGoogle Scholar
  10. [10]
    Sankovic, J. M., Kadambi, J. R., Mehta, M., Smith, W. A., and Wernet, M. P., PIV Investigations of the Flow Field in the Volute of a Rotary Blood Pump, ASME Journal of Fluids Engineering, Vol.126, No.5, pp.730–734, (2004).CrossRefGoogle Scholar
  11. [11]
    Yamane, T., Miyamoto, Y., Tajima, K., and Yamazaki, K., A Comparative Study Between Flow Visualization and Computational Fluid Dynamics Analysis for the Sun Medical Centrifugal Blood Pump, Artificial Organs, Vol.28, No.5, pp.458–466, (2004).CrossRefGoogle Scholar
  12. [12]
    Yamane, T., Kodama, T., Yamamoto, Y., Shinohara, T., and Nosé, Y., Flow Visualization in a Centrifugal Blood Pump with an Eccentric Inlet Port, Artificial Organs, Vol.28, No.6, pp.564–570, (2004).CrossRefGoogle Scholar
  13. [13]
    Day, S. W., and McDaniel, J. C., PIV Measurements of Flow in a Centrifugal Blood Pump: Steady Flow, ASME Journal of Biomechanical Engineering, Vol.127, No.2, pp. 244–253, (2005).CrossRefGoogle Scholar
  14. [14]
    Day, S. W., and McDaniel, J. C., PIV Measurements of Flow in a Centrifugal Blood Pump: Time-Varying Flow, ASME Journal of Biomechanical Engineering, Vol.127, No.2, pp.254–263, (2005).CrossRefGoogle Scholar
  15. [15]
    Wernet, M. P., Development of Digital Particle Imaging Velocimetry for Use in Turbomachinery, Experiments in Fluids, Vol.28, No.2, pp.97–115, (2000).ADSCrossRefGoogle Scholar
  16. [16]
    Westerweel, J., Fundamentals of Digital Particle Image Velocimetry, Measurement Science and Technology, Vol.8, No.12, pp.1379–1392, (1997).ADSCrossRefGoogle Scholar
  17. [17]
    Apel, J., Paul, R., Klaus, S., Siess, T., and Reul, H., Assessment of Hemolysis Related Quantities in a Microaxial Blood Pump by Computational Fluid Dynamics, Artificial Organs, Vol.25, No.5, pp.341–347, (2001).CrossRefGoogle Scholar
  18. [18]
    Wells, R. E., and Merrill, E. W., Shear Rate Dependence of the Viscosity of Whole Blood and Plasma, Science, Vol.133, No.3455, pp.763–764, (1961).ADSCrossRefGoogle Scholar
  19. [19]
    Eckmann, D. M., Bowers, S., Stecker, M., and Cheung, A. T., Hematocrit, Volume Expander, Temperature, and Shear Rate Effects on Blood Viscosity, Anesthesia & Analgesia, Vol.91, No.3, pp.539–545, (2000).CrossRefGoogle Scholar

Copyright information

© Science Press, Institute of Engineering Thermophysics, CAS and Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Xiaochen Yang
    • 1
  • Xingmin Gui
    • 2
  • Hui Huang
    • 1
  • Yongbin Shen
    • 1
  • Ziwen Yu
    • 1
  • Yan Zhang
    • 3
  1. 1.Beijing Institute of Aerospace Systems EngineeringBeijingChina
  2. 2.School of Jet PropulsionBeijing University of Aeronautics and AstronauticsBeijingChina
  3. 3.Department of Cardiovascular SurgeryFuwai HospitalBeijingChina

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