Acute Cardiovascular Effects of Marijuana Use
One out of 7 adults used marijuana in 2017.1 The concentration of tetrahydrocannabinol (THC), the primary psychoactive component of marijuana is increasing in commercially available products.2 However, there is little safety data available on the acute effects of cannabis outside of its psychoactive effects. One area of interest is the acute cardiovascular effects of marijuana given the ubiquitous presence of endocannabinoid receptors in the myocardium, coronary endothelium, and vascular endothelial and smooth muscle cells.3 We conducted a systematic review to examine the acute cardiovascular effects of marijuana use.
SK had the idea for the study. SK, MG, DR, DK, and TC created the study design. MG and DR collected the data. SK verified the data. MG, DR, DK, and SK analyzed and interpreted the data. SK and MG wrote and revised the manuscript. All authors critically revised the manuscript and approved the final version for submission. SK is the guarantor.
Compliance with Ethical Standards
Conflict of Interest
All authors declare that they have no conflict of interest.
Data set available from corresponding author on request.
The manuscript’s guarantor (SK) affirms that this manuscript is an honest, accurate, and transparent account of the study being reported; that no important aspects of the study have been omitted; and that any discrepancies from the study as planned have been explained.
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