Finding the Sweet Spot: the Last Blood Glucose Measured in the Hospital and 30-Day Outcomes—a Retrospective Study
Even though clinicians caring for hospitalized patients frequently encounter abnormal glucose values at hospital discharge, and hyperglycemia is associated with worse hospital outcomes, little data exists on the prognostic relevance of the last blood glucose (BG) measurement in the hospital.1, 2, 3 We parse the association between the last BG measurement in the hospital and 30-day readmission/mortality and test the following hypotheses: (1) Patients with dysglycemia on the last BG measurement in the hospital experience higher rates of 30-day death and readmissions. (2) The risk increases with the severity of dysglycemia (defined as glucose > 100 mg/dL or < 70 mg/dL) regardless of diagnosis of diabetes mellitus (DM).
We obtained institutional review board approval from the University of Minnesota and created an electronic medical record (EMR)–derived dataset of 126,527 emergent hospital admissions for 67,308 patients within a six-hospital network in the Twin Cities...
Resources used for the research reported in this publication were supported by the National Center for Advancing Translational Sciences of the National Institutes of Health Award Number UL1TR000114.
Dr. Sahni participated in study design, data analysis, and manuscript preparation. Dr. Arora participated in manuscript preparation. Dr. Simon participated in data analysis.
Compliance with Ethical Standards
Conflict of Interest
The authors declare that they do not have a conflict of interest.
The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
- 5.Yamada T, Shojima N, Noma H, Yamauchi T, Kadowaki T. Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials. Intensive Care Med. 2017;43(1). https://doi.org/10.1007/s00134-016-4523-0.