Journal of General Internal Medicine

, Volume 22, Issue 11, pp 1587–1595 | Cite as

Demystifying the NIH Grant Application Process

  • Karina M. Berg
  • Thomas M. Gill
  • Arleen F. Brown
  • Judy Zerzan
  • Joann G. Elmore
  • Ira B. Wilson
Clinical Review

Abstract

The process of applying to the National Institutes of Health (NIH) for grant funding can be daunting. The objective of this article is to help investigators successfully navigate the NIH grant application process. We focus on the practical aspects of this process, which are commonly learned through trial and error. Our target audience is generalist faculty and fellows who are applying for NIH funding to support their career development or a clinical research project.

KEY WORDS

clinical research academic medicine NIH funding grants 

References

  1. 1.
    Kotchen TA, Lindquist T, Malik K, Ehrenfeld E. NIH peer review of grant applications for clinical research. JAMA. 2004;291(7):836–43.PubMedCrossRefGoogle Scholar
  2. 2.
    Mandel HG, Vesell ES. From progress to regression: biomedical research funding. J Clin Invest. 2004;114(7):872–6.PubMedCrossRefGoogle Scholar
  3. 3.
    Marks AR. The economy of science. J Clin Invest. 2004;114(7):871.PubMedGoogle Scholar
  4. 4.
    Kahn CR. Picking a research problem—the critical decision. N Engl J Med. 1994;330:1530–3.PubMedCrossRefGoogle Scholar
  5. 5.
    Hulley S, et al. Designing Clinical Research, 2nd ed. Philadelphia: Lippincott Williams and Wilkins; 2001.Google Scholar
  6. 6.
    Steinman MA, Landefeld CS. Finding the target: getting started with quality of care and health services research. Qual Manag Health Care. 2002;10:19–24.PubMedGoogle Scholar
  7. 7.
    Inouye SK, Fiellin DA. An evidence-based guide to writing grant proposals for clinical research. Ann Int Med. 2005;15:274–82.Google Scholar
  8. 8.
    National Institutes of Health Office of Extramural Research. Research Project Success Rates by NIH Institute for 2006.Available at http://grants.nih.gov/grants/award/success/Success_ByIC.cfm. Accessed May 4, 2007.
  9. 9.
    ERA Commons. Computer Retrieval of Information on Scientific Projects. Available at http://crisp.cit.nih.gov. Accessed May 4, 2007.
  10. 10.
    Gill TM, McDermott MM, Ibrahim SA, Petersen LA, Doebbeling BN. Getting funded. Career development awards for aspiring clinical investigators. J Gen Intern Med. 2004;19:472–8.PubMedCrossRefGoogle Scholar
  11. 11.
    National Institutes of Health Office of Extramural Research. Available at http://grants1.nih.gov/grants/multi_pi/index.htm. Accessed May 4, 2007.
  12. 12.
    Bordage G, Dawson B. Experimental study design and grant writing in eight steps and 28 questions. Med Educ. 2003;37(4):376–85, Apr.PubMedCrossRefGoogle Scholar
  13. 13.
    Goldblatt D. How to get a grant funded. BMJ. 1998;317(7173):1647–8, Dec 12.PubMedGoogle Scholar
  14. 14.
    U.S. Department of Health and Human Services Public Health Service Grant Application (PHS 398). Available at http://grants1.nih.gov/grants/funding/phs398/phs398.doc. Accessed may 4, 2007.
  15. 15.
    National Institutes of Health Office of Extramural Research. SF424 (R&R) Application and Electronic Submission Information Available at http://grants.nih.gov/grants/funding/424/index.htm. Accessed May 4, 2007.
  16. 16.
    National Institutes of Health. NIH/AHRQ Confirms Plans to Transition the G7, G8, G11, G13, G20, S11, S21 and S22 to Electronic Applications and Announces Delay in Transition of K, F, T and Complex Grant Programs. Available at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-07-038.html. Accessed May 4, 2007.
  17. 17.
    NIH Transition Plan. http://era.nih.gov/ElectronicReceipt/files/NIH_Transition_Plan.pdf. Accessed May 4, 2007.
  18. 18.
    Electronic Research Administration. National Institutes of Health. Available at http://era.nih.gov. Accessed May 4, 2007.
  19. 19.
    National Institutes of Health Office of Extramural Research. Electronic Submission of Grant Applications. Available at http://era.nih.gov/electronicreceipt/preparing_grantsgov_reg.htm. Accessed May 4, 2007.
  20. 20.
    National Institutes of Health Office of Extramural Research. Electronic Submission of Grant Applications. Avoiding Common Errors. Available at http://era.nih.gov/ElectronicReceipt/avoiding_errors.htm. Accessed May 4, 2007.
  21. 21.
    National Institutes of Health. NIH Announces Updated Criteria for Evaluating Research Grant Applications. Available at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-05-002.html. Accessed May 4, 2007.
  22. 22.
    National Institute of Allergy and Infectious Diseases. National Institute of Health. NIAID Glossary of Funding and Policy Terms and Acronyms: N-Q Available at http://www.niaid.nih.gov/ncn/glossary/default5.htm#newpi. Accessed May 4, 2007.
  23. 23.
    National Heart, Lung, and Blood Institute. National Institutes of Health FY 2007 Funding and Operating Guidelines. Available at http://www.nhlbi.nih.gov/funding/policies/operguid.htm. Accessed May 4, 2007.
  24. 24.
    National Cancer Institute. National Institutes of Health. Extramural Funding Opportunities. NCI Funding Policy for FY 2007 Research Project Grant (RPG) AWARDS. Available at http://deainfo.nci.nih.gov/grantspolicies/FinalFundLtr.htm. Accessed May 4, 2007.
  25. 25.
    U.S. Department of Health and Human Services Public Health Service Grant Application (PHS 398) PART II Supplemental Instructions for Preparing the Human Subjects Section of the Research Plan. Available at http://grants1.nih.gov/grants/funding/phs398/HumanSubjects.doc. Accessed May 4, 2007.
  26. 26.
    United States Department of Health and Human Services. Office for Human Research Protections (OHRP). Available at http://www.hhs.gov/ohrp/. Accessed May 4, 2007.
  27. 27.
    National Institutes of Health. Change in Standing Receipt Dates for NIH/AHRQ/NIOSH Beginning in January 2007. Available at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-07-001.html. Accessed May 4, 2007.
  28. 28.
    Center for Scientific Review. Roster Index for Regular Standing Study Sections and Continuing SEPs. Available at http://www.csr.nih.gov/Roster_proto/sectionI.asp. Accessed May 4, 2007.
  29. 29.
    National Institutes of Health Office of Extramural Research. NIH Scientific Review Group (SRG) Roster Index. Available at http://era.nih.gov/roster/index.cfm. Accessed May 4, 2007.
  30. 30.
    NIH Extramural Nexus. Shortened Review Cycle for New Investigators Pilot Expanded. Available at http://grants.nih.gov/grants/partners/0307Nexus.htm#NewInvestigators. Accessed May 4, 2007.
  31. 31.
    Center for Scientific Review Resources For Applicants. Available at http://cms.csr.nih.gov/ResourcesforApplicants/. Accessed May 4, 2007.

Copyright information

© Society of General Internal Medicine 2007

Authors and Affiliations

  • Karina M. Berg
    • 1
  • Thomas M. Gill
    • 2
  • Arleen F. Brown
    • 3
  • Judy Zerzan
    • 4
  • Joann G. Elmore
    • 5
  • Ira B. Wilson
    • 6
    • 7
  1. 1.Division of General Internal MedicineAlbert Einstein College of Medicine and Montefiore Medical CenterBronxUSA
  2. 2.Yale University School of MedicineNew HavenUSA
  3. 3.Division of General Internal Medicine and Health Services ResearchUniversity of California at Los AngelesLos AngelesUSA
  4. 4.Health Services Research & DevelopmentVA Puget Sound Health Care SystemSeattleUSA
  5. 5.University of Washington School of Medicine, Harborview Medical CenterSeattleUSA
  6. 6.Institute for Clinical Research and Health Policy StudiesTufts-New England Medical CenterBostonUSA
  7. 7.Department of MedicineTufts-New England Medical CenterBostonUSA

Personalised recommendations