Journal of General Internal Medicine

, Volume 22, Issue 5, pp 681–684

Acute Kawasaki Disease: Not Just for Kids

Case Reports/Case Vignettes

Kawasaki Disease is a small-to-medium-vessel vasculitis that preferentially affects children. Kawasaki Disease can occur in adults, but the presentation may differ from that observed in children. Typical findings in both adults and children include fever, conjunctivitis, pharyngitis, and skin erythema progressing to a desquamating rash on the palms and soles. Adults more frequently present with cervical adenopathy (93% of adults vs. 15% of children), hepatitis (65% vs. 10%), and arthralgia (61% vs. 24–38%). In contrast, adults are less frequently affected by meningitis (10% vs. 34%), thrombocytosis (55% vs. 100%), and coronary artery aneurysms (5% vs. 18–25%). We report a case of acute Kawasaki Disease in a 24-year-old man who presented with rash, fever, and arthritis. He was successfully treated with high-dose aspirin and intravenous immunoglobulin (IVIG). Our case highlights the importance of considering Kawasaki Disease in adults presenting with symptoms commonly encountered in a general medical practice.

Key words

Kawasaki Disease adult coronary artery aneurysms vasculitis adenopathy arthritis mucocutaneous lymph node syndrome 

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Copyright information

© Society of General Internal Medicine 2007

Authors and Affiliations

  • Anne E. Wolff
    • 1
  • Karen E. Hansen
    • 2
  • Laura Zakowski
    • 2
    • 3
  1. 1.St. Louis UniversitySt. LouisUSA
  2. 2.University of WisconsinMadisonUSA
  3. 3.MadisonUSA

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