What’s in a Name? Use of Brand versus Generic Drug Names in United States Outpatient Practice
- 521 Downloads
The use of brand rather than generic names for medications can increase health care costs. However, little is known at a national level about how often physicians refer to drugs using their brand or generic names.
To evaluate how often physicians refer to drugs using brand or generic terminology.
Design and Participants
We used data from the 2003 National Ambulatory Medical Care Survey (NAMCS), a nationally representative survey of 25,288 community-based outpatient visits in the United States. After each visit, patient medications were recorded on a survey encounter form by the treating physician or transcribed from office notes.
Our main outcome measure was the frequency with which medications were recorded on the encounter form using their brand or generic names.
For 20 commonly used drugs, the median frequency of brand name use was 98% (interquartile range, 81–100%). Among 12 medications with no generic competition at the time of the survey, the median frequency of brand name use was 100% (range 92–100%). Among 8 medications with generic competition at the time of the survey (“multisource” drugs), the median frequency of brand name use was 79% (range 0–98%; P < .001 for difference between drugs with and without generic competition).
Physicians refer to most medications by their brand names, including drugs with generic formulations. This may lead to higher health care costs by promoting the use of brand-name products when generic alternatives are available.
Key wordsdrug labeling drug industry prescriptions, drug drugs, generic names prescription fees ambulatory care
- 5.National Center for Health Statistics. Public use micro-data file documentation, National Ambulatory Medical Care Survey, 2003. Hyattsville, MD: National Technical Information Service; 2005. Available at http://www.cdc.gov/nchs/about/major/ahcd/ahcd1.htm.
- 6.National Center for Health Statistics. Using ultimate cluster models with NAMCS and NHAMCS public use files. Available at: http://www.cdc.gov/nchs/data/ahcd/ultimatecluster.pdf. Accessed 19 May, 2005.
- 7.Mathews AW. When a drug maker creates a new pill, Uncle Sam vets name. FDA tries to avoid mix-ups, similar monikers, dupes; Bonviva becomes Boniva. Wall Street J. March 17, 2006:1.Google Scholar
- 16.Testimony of the Generic Pharmaceutical Association (GPhA) Before the Subcommittee on Health, House Committee of Energy and Commerce, May 18, 2005. Available at: http://energycommerce.house.gov/108/Hearings/05182005hearing1526/Jaeger.pdf#search=%22generic%20substitution%20utilization%22. Accessed 23 October, 2006.
- 17.Congressional Budget Office. How Increased Competition from Generic Drugs Has Affected Prices and Returns in the Pharmaceutical Industry. Available at: http://www.cbo.gov/ftpdocs/6xx/doc655/pharm.pdf. Accessed 13 July, 2006.
- 20.Accreditation Council for Continuing Medical Education. Standards for Commercial Support. Available at: http://www.accme.org/dir_docs/doc_upload/68b2902a-fb73-44d1-8725-80a1504e520c_uploaddocument.pdf. Accessed 13 July, 2006.