Closed Cyst Resection for Liver Hydatid Disease: a New Standard
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Although radical resections are recommended for the surgical management of liver hydatid disease (LHD), whether closed (CCR) or opened (OCR) cyst resections should be performed remains unclear. The aim of this study was to compare the postoperative and long-term outcomes of CCR and OCR for primary and recurrent LHD.
Materials and Methods
Medical charts of patients who underwent surgery at a single centre were retrospectively reviewed and compared with respect to major postoperative complications and recurrence rates.
Seventy-nine CCRs and 37 OCRs were included. The major morbidity rates were 19% and 5% in the OCR and CCR groups, respectively (P = 0.036). In multivariate analysis, OCR (P = 0.030, OR = 5.37) and the operative time (P < 0.001, OR = 18.88) were the only independent predictors of major complications. The 5-year and 10-year recurrence rates were both 0% in the CCR group compared to 18% and 27%, respectively, in the OCR group (P < 0.001). The mean time to recurrence was 10.5 (± 8) years.
Closed cyst resection for LHD is a safe and effective approach with a low risk of recurrence. Considering that recurrence could appear more than 10 years after surgery, follow-up of patients should be adapted.
KeywordsHepatic hydatidosis Liver Parasitic diseases
Compliance with Ethical Standards
Conflict of Interest
The authors declare that they have no conflict of interest.
- 2.Torgerson PR., Devleesschauwer B., Praet N., Speybroeck N., Willingham AL., Kasuga F., et al. World Health Organization Estimates of the Global and Regional Disease Burden of 11 Foodborne Parasitic Diseases, 2010: A Data Synthesis. PLOS Med. 2015;12(12):e1001920. https://doi.org/10.1371/journal.pmed.1001920.CrossRefPubMedPubMedCentralGoogle Scholar
- 10.Bourgeon R., Mouuiel J. The merits of radical surgery in the treatment of hydatid cysts of the liver. Memoires Acad Chir Fr. 1964;90:355–61.Google Scholar
- 11.von Elm E., Altman DG., Egger M., Pocock SJ., Gøtzsche PC., Vandenbroucke JP., et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies. Ann Intern Med. 2007;147(8):573. https://doi.org/10.7326/0003-4819-147-8-200710160-00010.CrossRefGoogle Scholar
- 24.Kern P., Menezes da Silva A., Akhan O., Müllhaupt B., Vizcaychipi KA., Budke C., et al. The Echinococcoses. Advances in Parasitology, vol. 96. Elsevier; 2017. p. 259–369.Google Scholar