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Laparoscopic Liver Resection Difficulty Score—a Validation Study

  • Ser Yee LeeEmail author
  • Brian K. P. Goh
  • Gholami Sepideh
  • John C. Allen
  • Ryan P. Merkow
  • Jin Yao Teo
  • Deepa Chandra
  • Ye Xin Koh
  • Ek Khoon Tan
  • Juinn Haur Kam
  • Peng Chung Cheow
  • Pierce K. H. Chow
  • London L. P. J. Ooi
  • Alexander Y. F. Chung
  • Michael I. D’Angelica
  • William R. Jarnagin
  • T. Peter Kingham
  • Chung Yip Chan
Original Article
  • 73 Downloads

Abstract

Objective(s)

The technical complexity of laparoscopic liver resection (LLR) poses unique challenges distinct from open surgery. An objective scoring system was developed that preoperatively quantifies the difficulty of LRR to help guide surgeon decision-making regarding the feasibility and safety of minimally invasive approaches. The aim of this multiinstitutional study was to externally validate this scoring system.

Methods

Patients who underwent LLR at two institutions were reviewed. LLR difficulty score (LDS) was calculated based on patient, tumor, and anatomic characteristics by two independent, blinded hepatobiliary surgeons. Surrogates of case complexity (e.g., conversion rate, operative time) were used for validation of this index.

Results

From 2006 to 2016, 444 LLR were scored as low (n = 94), intermediate (n = 98), and high difficulty (n = 152) with respective conversion rates of 5.3%, 15.7%, and 25%. Cases of higher LDS correlated with larger mean blood loss (203 ml vs. 331 ml vs. 635 ml). Mean operative and Pringle maneuver used were associated with increasing LDS (155 min vs. 202 min vs. 315 min and 14.4% vs. 29.7% vs. 45.1% respectively). These operative surrogates of difficulty correlated significantly with the LDS (all p < 0.0001).

Conclusions

This comprehensive external validation of the LDS is robust and applicable in diverse patient populations. This LDS serves as a useful objective predictor of technical difficulty for LLR to help surgeons in selecting patients according to their individual operative experience and is valuable for preoperative risk estimation and stratification in randomized trials.

Keywords

Laparoscopic liver resection Difficulty score 

Notes

Author Contributions

All the authors have made substantial contributions to the conception or design of the work. They have all contributed substantially to the acquisition, analysis, or interpretation of data for the work. This included drafting the manuscript and/or revising it critically for important intellectual content. All authors have read and given the final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Supplementary material

11605_2018_4036_MOESM1_ESM.docx (392 kb)
ESM 1 (DOCX 392 kb)

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Copyright information

© The Society for Surgery of the Alimentary Tract 2018

Authors and Affiliations

  • Ser Yee Lee
    • 1
    • 2
    Email author
  • Brian K. P. Goh
    • 1
    • 2
  • Gholami Sepideh
    • 3
  • John C. Allen
    • 2
  • Ryan P. Merkow
    • 3
  • Jin Yao Teo
    • 1
  • Deepa Chandra
    • 4
  • Ye Xin Koh
    • 1
    • 2
  • Ek Khoon Tan
    • 1
    • 2
  • Juinn Haur Kam
    • 1
  • Peng Chung Cheow
    • 1
    • 2
  • Pierce K. H. Chow
    • 1
    • 2
    • 5
  • London L. P. J. Ooi
    • 1
    • 2
  • Alexander Y. F. Chung
    • 1
    • 2
  • Michael I. D’Angelica
    • 3
  • William R. Jarnagin
    • 3
  • T. Peter Kingham
    • 3
  • Chung Yip Chan
    • 1
    • 2
  1. 1.Department of Hepatopancreatobiliary and Transplant SurgerySingapore General HospitalSingaporeSingapore
  2. 2.Duke-National University of Singapore (NUS) Medical SchoolSingaporeSingapore
  3. 3.Department of SurgeryMemorial Sloan Kettering Cancer CenterNew YorkUSA
  4. 4.Yong Loo Lin School of MedicineNational University of Singapore (NUS)SingaporeSingapore
  5. 5.Division of Surgical OncologyNational Cancer Center SingaporeSingaporeSingapore

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