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Comparison of Long-term Quality of Life in Patients with Esophageal Cancer after Ivor-Lewis, Mckeown, or Sweet Esophagectomy

  • Yu-Shang Yang
  • Qi-Xin Shang
  • Yong Yuan
  • Xiao-Ying Wu
  • Wei-Peng Hu
  • Long-Qi Chen
Original Article
  • 24 Downloads

Abstract

Background

The aim of this study was to compare the long-term quality of life (QoL) in patients after Sweet, Ivor-Lewis, or Mckeown esophagectomy.

Methods

Esophageal cancer patients after Sweet, Ivor-Lewis, or Mckeown esophagectomy from 2010 to 2012 were included. QoL was assessed according to the European Organization for Research and Treatment of Cancer general questionnaire: QLQ-C30 and esophagus-specific questionnaire: QLQ-OES18.

Results

A total of 126 qualified patients who have been alive for more than 3 years without tumor recurrence were divided into three groups: the Sweet group (n = 40), Ivor-Lewis group (n = 38), and Mckeown group (n = 48). Among these three groups, the QLQ-C30 mean scores of global health status, functional and symptom scales, and general QoL were similar. The symptom scales of QLQ-OSE18 showed that patients who had a Mckeown operation experienced more problem of eating (P = 0.029), choking when swallowing (P = 0.010) and coughing (P = 0.016), while patients undergoing Sweet operation complained more symptom of reflux (P = 0.003) and pain (P = 0.000).

Conclusions

All three types of esophagectomy provided a generally good long-term QoL. However, patients in Sweet and Mckeown group tend to suffer from a higher symptomatic burden as compared to Ivor-Lewis approach.

Keywords

Esophageal cancer Quality of life (QoL) QLQ-C30 QLQ-OES18 Esophagectomy 

Notes

Authors’ Contributions

(I) Conception and design: Long-Qi Chen, Yu-Shang Yang, and Yong Yuan;

(II) Administrative support: Wei-Peng Hu and Yu-Shang Yang;

(III) Provision of study materials or patients: Qi-Xin Shang and Yu-Shang Yang;

(IV) Collection and assembly of data: Yu-Shang Yang, Xiao-Ying Wu, and Qi-Xin Shang;

(V) Data analysis and interpretation: Qi-Xin Shang, Wei-Peng Hu, and Yong Yuan;

(VI) Manuscript writing: All authors;

(VII) Final approval of manuscript: All authors.

Compliance with Ethical Standards

Competing Interests

The authors declare that they have no competing interests.

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Copyright information

© The Society for Surgery of the Alimentary Tract 2018

Authors and Affiliations

  • Yu-Shang Yang
    • 1
  • Qi-Xin Shang
    • 1
  • Yong Yuan
    • 1
  • Xiao-Ying Wu
    • 1
  • Wei-Peng Hu
    • 1
  • Long-Qi Chen
    • 1
  1. 1.Department of Thoracic SurgeryWest China Hospital of Sichuan UniversityChengduChina

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