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Slow Gait Speed Is a Risk Factor for Complications After Hepatic Resection

  • Shinji Itoh
  • Tomoharu Yoshizumi
  • Kazuhisa Sakata
  • Takashi Motomura
  • Yohei Mano
  • Takeo Toshima
  • Norifumi Harimoto
  • Noboru Harada
  • Toru Ikegami
  • Yuji Soejima
  • Ryuichi Kusaba
  • Takahide Kamishima
  • Akihiro Nishie
  • Yoshihiko Maehara
Original Article
  • 32 Downloads

Abstract

Purpose

The aims of this study were to clarify the relationship of gait speed, hand grip strength, and skeletal muscle mass with complications after hepatic resection and to identify risk factors for complications in patients who underwent hepatic resection.

Methods

We evaluated the risk factors for complications after hepatic resection in 154 consecutive patients. Preoperative factors included gait speed, hand grip strength, and skeletal muscle mass. The gait speed and hand grip strength of patients were measured by physical therapists, and skeletal muscle mass was measured by computed tomography. Multivariate logistic regression analyses using preoperative factors were performed to assess predictors of the development of complications after hepatic resection.

Results

Thirty-three patients (21.4%) developed complications after hepatic resection. These patients had a significantly lower serum albumin level (p = 0.015), slower gait speed (p = 0.007), higher rate of hepatic resection ≥ 2 Couinaud segments (p = 0.014), and lower rate of laparoscopic hepatic resection (p = 0.017) than patients without complications. Multivariate analysis revealed that a gait speed ≤ 1.10 m/s and a serum albumin level of ≤ 4.0 g/dl were independent risk factors for complications after hepatic resection.

Conclusions

Slow gait speed and low serum albumin level are significant risk factors for complications after hepatic resection. These data will be helpful for perioperative patient management.

Keywords

Gait speed Complication Hepatic resection Frailty 

Notes

Acknowledgements

We thank Angela Morben, DVM, ELS, from Edanz Group (www.edanzediting.com/ac) for editing a draft of this manuscript.

Author Contributions

S.I. participated in study conception and design, analysis, and drafting of the article.

T.Y. participated in study conception and design, and critical revision of the manuscript.

K.S. participated in acquisition of data, analysis, and interpretation of data.

T.M. participated in acquisition of data, analysis, and interpretation of data.

Y.M. participated in acquisition of data, analysis, and interpretation of data.

T.T. participated in acquisition of data, analysis, and interpretation of data.

N.H. participated in acquisition of data, analysis, and interpretation of data.

N. Harada participated in acquisition of data, analysis, and interpretation of data.

T.I. participated in acquisition of data, analysis, and interpretation of data.

Y.S. participated in acquisition of data, analysis, and interpretation of data.

R.K. participated in acquisition of data, analysis, and interpretation of data.

T.K. participated in acquisition of data, analysis, and interpretation of data.

A.N. participated in acquisition of data, analysis, and interpretation of data.

Y. Maehara participated in critical revision of the manuscript.

Supplementary material

11605_2018_3993_MOESM1_ESM.doc (54 kb)
Supplementary Figure 1 (DOC 54 kb)

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Copyright information

© The Society for Surgery of the Alimentary Tract 2018

Authors and Affiliations

  • Shinji Itoh
    • 1
  • Tomoharu Yoshizumi
    • 1
  • Kazuhisa Sakata
    • 1
  • Takashi Motomura
    • 1
  • Yohei Mano
    • 1
  • Takeo Toshima
    • 1
  • Norifumi Harimoto
    • 1
  • Noboru Harada
    • 1
  • Toru Ikegami
    • 1
  • Yuji Soejima
    • 1
  • Ryuichi Kusaba
    • 2
  • Takahide Kamishima
    • 2
  • Akihiro Nishie
    • 3
  • Yoshihiko Maehara
    • 1
  1. 1.Department of Surgery and Science, Graduate School of Medical SciencesKyushu UniversityFukuokaJapan
  2. 2.Department of Rehabilitation MedicineKyushu University HospitalFukuokaJapan
  3. 3.Department of Clinical Radiology, Graduate School of Medical SciencesKyushu UniversityFukuokaJapan

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