Single-Port Inflatable Mediastinoscopy Combined With Laparoscopic-Assisted Small Incision Surgery for Radical Esophagectomy Is an Effective and Safe Treatment for Esophageal Cancer

  • Xiaojin Wang
  • Xiaojian Li
  • Hua Cheng
  • Bin Zhang
  • Hongcheng Zhong
  • Ruiqi Wang
  • Beilong Zhong
  • Qingdong CaoEmail author
Original Article



We previously developed a novel non-trans thoracic esophagectomy, the single-port inflatable mediastinoscopy combined with laparoscopy for the radical esophagectomy of esophageal cancer. The purpose of this study was to report its therapeutic efficacy and safety.


From May 2016 to August 2017, we have completed 80 cases of radical resection of esophageal carcinoma using this novel surgical technique. The intraoperative findings and postoperative complications were reported.


The operation was successfully performed in all patients except for one patient switched from laparoscopic-assisted operation to open surgery. The mean operation duration was 191.4 ± 27 min, and the mean intraoperative blood loss was 147.3 ± 28.9 mL. The mean number of removed lymph node was 21.9 ± 4.1. Five patients (6.4%) who had preoperative type I respiratory failure needed to stay in the intensive care unit for 24 h postoperatively. Postoperative complications included anastomotic leakage (8.9%), anastomotic stricture (21.25%), pleural effusion (9%), and hoarseness postoperative hoarseness (18.8%). The incidence of hoarseness at 3 months postoperation was reduced to 3.8%. All the complications were Clavien-Dindo grades I–III. There were no perioperative death and postoperative cardiopulmonary complications.


These results showed that the single-port inflatable mediastinoscopy combined with laparoscopy is feasible for radical esophagectomy and possesses good therapeutic efficacy and safety.


Esophageal cancer Esophagectomy Non-thoracotomy Inflatable mediastinoscopy Laparoscopy 



This study was supported by the Talents start-up funding of Sun Yat-sen University.

Compliance with Ethical Standards

Conflicts of Interest

The authors declare that there are no conflicts of interest.


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Copyright information

© The Society for Surgery of the Alimentary Tract 2019

Authors and Affiliations

  • Xiaojin Wang
    • 1
  • Xiaojian Li
    • 1
  • Hua Cheng
    • 1
  • Bin Zhang
    • 1
  • Hongcheng Zhong
    • 1
  • Ruiqi Wang
    • 1
  • Beilong Zhong
    • 1
  • Qingdong Cao
    • 1
    Email author
  1. 1.Department of Cardiothoracic SurgeryThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhaiChina

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