Journal of Gastrointestinal Surgery

, Volume 21, Issue 10, pp 1700–1712 | Cite as

Association Between Obesity and Wound Infection Following Colorectal Surgery: Systematic Review and Meta-Analysis

  • Usha Gurunathan
  • Simone Ramsay
  • Goran Mitrić
  • Mandy Way
  • Leesa Wockner
  • Paul Myles
Review Article

Abstract

Background

The aim of this meta-analysis is to comprehensively review and quantify the excess risk of surgical site infections (SSI) in obese patients following colorectal surgery.

Methods

A systematic electronic search of the MEDLINE and EMBASE databases identified studies that investigated the association of obesity, defined by body mass index (BMI) with SSI among colorectal surgery patients.

Results

Twelve studies were included in the final analysis. Patients with BMI ≥30 kg/m2 were at 1.5 times (pooled OR 1.51, 95% CI: 1.39, 1.63, p < 0.001) higher odds of developing SSI after colorectal surgery when compared to BMI <30 kg/m2. Subgroup analysis of the eight studies that investigated only elective procedures showed that the odds of developing SSI when BMI ≥30 kg/m2 is 1.6 times that of those with BMI <30 kg/m2 (pooled OR 1.60; 95% CI 1.34, 1.86; p < 0.001). The odds of having SSI when BMI is 25–29.9 kg/m2 are 1.2 times than those with BMI <25 kg/m2 (pooled OR 1.17; 95% CI 1.07, 1.28; p < 0.001).

Conclusion

Overweight and obese patients carry at least 20% and 50% higher odds of developing SSI after colorectal surgery compared to normal weight patients, respectively.

Keywords

Obesity Surgical site infection Colorectal surgery 

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Copyright information

© The Society for Surgery of the Alimentary Tract 2017

Authors and Affiliations

  1. 1.Department of Anaesthesia and Perfusion Services & Department of SurgeryThe Prince Charles Hospital & University of QueenslandBrisbaneAustralia
  2. 2.Statistics Unit QIMR Berghofer Medical Research InstituteBrisbaneAustralia
  3. 3.Department of Anaesthesia and Perioperative MedicineAlfred Hospital & Monash UniversityMelbourneAustralia

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