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Journal of Gastrointestinal Surgery

, Volume 20, Issue 12, pp 2035–2051 | Cite as

Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage

  • Sami A. Chadi
  • Abe Fingerhut
  • Mariana Berho
  • Steven R. DeMeester
  • James W. Fleshman
  • Neil H. Hyman
  • David A. Margolin
  • Joseph E. Martz
  • Elisabeth C. McLemore
  • Daniela Molena
  • Martin I. Newman
  • Janice F. Rafferty
  • Bashar Safar
  • Anthony J. Senagore
  • Oded Zmora
  • Steven D. WexnerEmail author
Article

Abstract

Anastomotic leaks represent one of the most alarming complications following any gastrointestinal anastomosis due to the substantial effects on post-operative morbidity and mortality of the patient with long-lasting effects on the functional and oncologic outcomes. There is a lack of consensus related to the definition of an anastomotic leak, with a variety of options for prevention and management. A number of patient-related and technical risk factors have been found to be associated with the development of an anastomotic leak and have inspired the development of various preventative measures and technologies. The International Multispecialty Anastomotic Leak Global Improvement Exchange group was convened to establish a consensus on the definition of an anastomotic leak as well as to discuss the various diagnostic, preventative, and management measures currently available.

Keywords

Gastrointestinal anastomotic leakage Review Morbidity International Multispecialty Anastomotic Leak Global Improvement Exchange Consensus 

Notes

Compliance with Ethical Standards

NOVADAQ provided funding for travel and and/or honoraria to the IMAGInE consensus group for the development of this document. The lead author was compensated for the preparation of this mansucript. M Berho is a paid consultant for NOVADAQ; S DeMeester is a paid lecturer for NOVADAQ; D Molena is a paid educational presentation developer for NOVADAQ; A Senagore is a paid lecturer for NOVADAQ; SD Wexner is a paid consultant for NOVADAQ and Karl Storz Endoscopy; O Zmora is a paid lecture and lectures and paid educational lecture developer for NOVADAQ.

Disclosures

NOVADAQ Corporation reviewed the final manuscript but did not have any role in the preparation of the manuscript, selection of the speakers, topics, or content of the symposium, and had no editing privileges. NOVADAQ Corporation did not influence the manuscript.

Authorship Contribution

All authors have made substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; drafting the work or revising it critically for important intellectual content; final approval of the version to be published; and agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. NOVADAQ Corporation made no contributions to this manuscript.

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Copyright information

© The Society for Surgery of the Alimentary Tract 2016

Authors and Affiliations

  • Sami A. Chadi
    • 1
    • 2
    • 3
  • Abe Fingerhut
    • 4
    • 5
  • Mariana Berho
    • 6
  • Steven R. DeMeester
    • 7
  • James W. Fleshman
    • 8
  • Neil H. Hyman
    • 9
  • David A. Margolin
    • 10
  • Joseph E. Martz
    • 11
  • Elisabeth C. McLemore
    • 12
  • Daniela Molena
    • 13
  • Martin I. Newman
    • 14
  • Janice F. Rafferty
    • 15
  • Bashar Safar
    • 16
  • Anthony J. Senagore
    • 17
  • Oded Zmora
    • 18
  • Steven D. Wexner
    • 1
    Email author
  1. 1.Department of Colorectal SurgeryCleveland Clinic FloridaWestonUSA
  2. 2.Division of General SurgeryUniversity Health NetworkTorontoCanada
  3. 3.Department of SurgeryUniversity of TorontoTorontoCanada
  4. 4.Section for Surgical Research, Department of SurgeryMedical University of GrazGrazAustria
  5. 5.First Department of Surgery, Hippokration University HospitalUniversity of AthensAthensGreece
  6. 6.Department of PathologyCleveland Clinic FloridaWestonUSA
  7. 7.Department of Surgery, Keck School of MedicineUniversity of Southern CaliforniaLos AngelesUSA
  8. 8.Department of SurgeryBaylor University Medical Center at DallasDallasUSA
  9. 9.Department of SurgeryUniversity of Chicago MedicineChicagoUSA
  10. 10.Department of Colon and Rectal SurgeryOchsner Clinic FoundationNew OrleansUSA
  11. 11.Division of Colorectal SurgeryMount Sinai Beth IsraelNew YorkUSA
  12. 12.Department of Surgery, Colorectal SurgeryKaiser Permanente Los Angeles Medical CenterLos AngelesUSA
  13. 13.Division of Thoracic Surgery, Department of SurgeryJohns Hopkins UniversityBaltimoreUSA
  14. 14.Department of Plastic and Reconstructive SurgeryCleveland Clinic FloridaWestonUSA
  15. 15.Department of SurgeryUniversity of Cincinnati College of MedicineCincinnatiUSA
  16. 16.Department of SurgeryJohns Hopkins University School of MedicineBaltimoreUSA
  17. 17.Department of Surgery, School of MedicineCase Western Reserve UniversityClevelandUSA
  18. 18.Department of Surgery, Sackler School of MedicineSheba Medical CenterTel AvivIsrael

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