Journal of Gastrointestinal Surgery

, Volume 19, Issue 5, pp 858–865 | Cite as

Minimally Invasive Resection of Choledochal Cyst: a Feasible and Safe Surgical Option

  • Georgios Antonios Margonis
  • Gaya Spolverato
  • Yuhree Kim
  • Hugo Marques
  • George Poultsides
  • Shishir Maithel
  • Luca Aldrighetti
  • Todd W. Bauer
  • Nicolas Jabbour
  • T. Clark Gamblin
  • Kevin Soares
  • Timothy M. Pawlik
Original Article

Abstract

Background

The use of minimally invasive surgery (MIS) for choledochal cyst (CC) has not been well documented. We sought to define the overall utilization and outcomes associated with the use of the open versus MIS approach for CC. We examined the factors associated with receipt of MIS for CC, as well as characterized perioperative and long-term outcomes following open versus MIS for CC.

Methods

Between 1972 and 2014, a total of 368 patients who underwent resection for CC were identified from an international, multicenter database. A 2:1 propensity score matching was used to create comparable cohorts of patients to assess the effect of MIS on short-term outcomes.

Results

Three hundred thirty-two patients had an open procedure, whereas 36 patients underwent an MIS approach. Children were more likely to be treated with a MIS approach (children, 24.0 % vs. adults, 2.1 %; P < 0.001). Conversely, patients who had any medical comorbidity were less likely to undergo MIS surgery (open, 26.2 % vs. MIS, 2.8 %; P = 0.002). In the propensity-matched cohort, MIS resection was associated with decreased length of stay (open, 7 days vs. MIS, 5 days), lower estimated blood loss (open, 50 mL vs. MIS, 17.5 mL), and longer operative time (open, 237 min vs. MIS, 301 min) compared with open surgery (all P < 0.05). The overall and degree of complication did not differ between the open (grades I–II, n = 13; grades III–IV, n = 15) versus MIS (grades I–II, n = 5; grades III–IV, n = 5) cohorts (P = 0.85). Five-year overall survival was 98.6 % (open, 98.0 % vs. MIS, 100.0 %; P = 0.45); no patient who underwent MIS developed a subsequent cholangiocarcinoma.

Conclusions

MIS resection of CC was demonstrated to be a feasible and safe approach with acceptable short-term outcomes in the pediatric population. MIS for benign CC disease was associated with similar perioperative morbidity but a shorter length of stay and a lower blood loss when compared with open resection.

Keyword

Choledochal cyst Surgery Laparoscopy Mini-invasive surgery 

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Copyright information

© The Society for Surgery of the Alimentary Tract 2014

Authors and Affiliations

  • Georgios Antonios Margonis
    • 1
  • Gaya Spolverato
    • 1
  • Yuhree Kim
    • 1
  • Hugo Marques
    • 2
  • George Poultsides
    • 3
  • Shishir Maithel
    • 4
  • Luca Aldrighetti
    • 5
  • Todd W. Bauer
    • 6
  • Nicolas Jabbour
    • 7
  • T. Clark Gamblin
    • 8
  • Kevin Soares
    • 1
  • Timothy M. Pawlik
    • 1
  1. 1.Department of SurgeryThe Johns Hopkins University School of MedicineBaltimoreUSA
  2. 2.Curry Cabral HospitalLisbonPortugal
  3. 3.Stanford UniversityStanfordUSA
  4. 4.Emory UniversityAtlantaUSA
  5. 5.Ospedale San RaffaeleMilanItaly
  6. 6.University of VirginiaCharlottesvilleUSA
  7. 7.Universite Catholique de LouvainBrusselsBelgium
  8. 8.Medical College of WisconsinMilwaukeeUSA

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