Journal of Gastrointestinal Surgery

, Volume 12, Issue 3, pp 510–517 | Cite as

Use of Antireflux Medication After Antireflux Surgery

  • Bas P. L. WijnhovenEmail author
  • Carolyn J. Lally
  • John J. Kelly
  • Jennifer C. Myers
  • David I. Watson
original article



It is claimed that a substantial number of patients who undergo antireflux surgery use antireflux medication postoperatively. This study was aimed to determine the prevalence and underlying reasons for antireflux medication usage in patients after surgery.

Materials and Methods

A questionnaire on the usage of antireflux medication was sent to 1,008 patients identified from a prospective database of patients who had undergone a laparoscopic antireflux procedure.


A total of 844 patients (84%) returned the questionnaire. Mean follow-up was 5.9 years after surgery. A single or combination of medications was being taken by 312 patients (37%): 82% proton pump inhibitors, 9% H2-blockers and 34% antacids. Fifty-two patients (17%) had never stopped taking medication, whereas 260 patients (83%) restarted medication at a mean of 2.5 years after surgery. Return of the same (31%) or different (49%) symptoms were the commonest reasons for taking medication, whereas 20% were asymptomatic or had other reasons for medication use. Postoperative 24-hour pH studies were abnormal in 16/61 patients (26%) on medication and in 5/78 patients (6%) not taking medication.


Antireflux medication is frequently taken by many patients for various symptoms after antireflux surgery. Symptomatic patients should be properly investigated before antireflux medications are prescribed.


Medication Gastroesophageal reflux Fundoplication 



Lorraine Sheehan-Hennessy and Emily Moskwa are greatly acknowledged for their assistance with the mail out of the questionnaires and gathering of the data. Dr Richard Woodman is also greatly acknowledged for statistical analysis of the data.


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Copyright information

© The Society for Surgery of the Alimentary Tract 2007

Authors and Affiliations

  • Bas P. L. Wijnhoven
    • 1
    Email author
  • Carolyn J. Lally
    • 1
    • 2
  • John J. Kelly
    • 1
  • Jennifer C. Myers
    • 2
  • David I. Watson
    • 1
  1. 1.Flinders University Department of SurgeryFlinders Medical CentreBedford ParkAustralia
  2. 2.University of Adelaide Discipline of SurgeryRoyal Adelaide HospitalAdelaideAustralia

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