Journal of Gastrointestinal Surgery

, Volume 11, Issue 12, pp 1579–1588 | Cite as

Laparoscopic Nissen Fundoplication Effectively Relieves Symptoms in Patients with Laryngopharyngeal Reflux

  • Robert A. Catania
  • Stephen M. Kavic
  • J. Scott Roth
  • Tommy H. Lee
  • Tanya Meyer
  • George T. Fantry
  • Paul F. Castellanos
  • Adrian ParkEmail author



The utility of laparoscopic Nissen fundoplication in the treatment of laryngopharyngeal reflux symptoms remains controversial. We hypothesized that a carefully selected population with these symptoms would benefit from antireflux surgery.

Materials and Methods

Sixty-one consecutive patients have undergone antireflux surgery for laryngopharyngeal reflux at a single institution. Preoperative evaluation including upper endoscopy, laryngoscopy, and 24-h ambulatory pharyngeal pH probe monitoring confirmed the diagnosis. Patients completed two validated symptom assessment instruments preoperatively and at multiple time points postoperatively.


Patients were followed for up to 3 years with a mean follow-up of 15.2 months. A significant improvement in reflux symptom index score (preoperative = 31.5 ± 7.4 vs 3 years = 12.4 ± 10.9, p < 0.01), laryngopharyngeal reflux health-related quality of life overall score (preoperative = 55.0 ± 26.0 vs 3 years = 11.3 ± 13.9, p < 0.01), and symptom domain scores (voice, cough, throat clearing, and swallowing) occured within 1 month of surgery and remained improved over the course ofthe study.


Laparoscopic Nissen fundoplication is effective in relieving the symptoms of laryngopharyngeal reflux in a carefully selected patient population. Benefits are seen within 1 month of surgery and persist for at least 3 years.


Laryngopharyngeal reflux Laparoscopic Nissen fundoplication Quality of life Antireflux surgery Outcomes 



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Copyright information

© The Society for Surgery of the Alimentary Tract 2007

Authors and Affiliations

  • Robert A. Catania
    • 1
  • Stephen M. Kavic
    • 1
  • J. Scott Roth
    • 1
  • Tommy H. Lee
    • 1
  • Tanya Meyer
    • 2
  • George T. Fantry
    • 3
  • Paul F. Castellanos
    • 4
  • Adrian Park
    • 1
    Email author
  1. 1.Division of General SurgeryUniversity of Maryland Medical CenterBaltimoreUSA
  2. 2.Department of OtolaryngologyUniversity of Maryland Medical CenterBaltimoreUSA
  3. 3.Department of GastroenterologyUniversity of Maryland Medical CenterBaltimoreUSA
  4. 4.Division of OtolaryngologyUniversity of Alabama at BirminghamBirminghamUSA

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