Journal of Gastrointestinal Surgery

, Volume 11, Issue 5, pp 555–561

Hepaticojejunostomy—Analysis of Risk Factors for Postoperative Bile Leaks and Surgical Complications

  • Dalibor Antolovic
  • Moritz Koch
  • Luis Galindo
  • Sandra Wolff
  • Emira Music
  • Peter Kienle
  • Peter Schemmer
  • Helmut Friess
  • Jan Schmidt
  • Markus W. Büchler
  • Jürgen Weitz
Article

Abstract

Anastomoses between the jejunum and the bile duct are an important component of many surgical procedures; however, risk factors for clinically relevant bile leaks have not yet been adequately defined. The objective of this study was to describe the incidence of bile leaks after hepaticojejunostomy and to define predictive factors associated with this risk and with surgical morbidity. Between October 2001 and April 2004, hepaticojejunostomies were performed in 519 patients in a standardized way. Patient- and treatment-related data were documented prospectively. A bile leak was defined as bilirubin concentration in the drains exceeding serum bilirubin with a consecutive change of clinical management or occurrence of a bilioma necessitating drainage. Surgical morbidity occurred in 15% of patients, the incidence of a bile leak was 5.6%. Multivariate analysis confirmed preoperative radiochemotherapy, preoperative low cholinesterase levels, biliary complications after liver transplantation necessitating a hepaticojejunostomy, and simultaneous liver resection as risk factors for bile leakages, whereas biliary complications after liver transplantation necessitating hepaticojejunostomy, simultaneous liver resection, and diabetes mellitus were significantly associated with postoperative surgical morbidity. Our results demonstrate that hepaticojejunostomy is a safe procedure if performed in a standardized fashion. The above found factors may help to better predict the risk for complications after hepaticojejunostomy.

Keywords

Hepaticojejunostomy Bile leak Risk factors Surgical morbidity 

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Copyright information

© The Society for Surgery of the Alimentary Tract 2007

Authors and Affiliations

  • Dalibor Antolovic
    • 1
  • Moritz Koch
    • 1
  • Luis Galindo
    • 1
  • Sandra Wolff
    • 1
  • Emira Music
    • 1
  • Peter Kienle
    • 1
  • Peter Schemmer
    • 1
  • Helmut Friess
    • 1
  • Jan Schmidt
    • 1
  • Markus W. Büchler
    • 1
  • Jürgen Weitz
    • 1
  1. 1.Department of SurgeryUniversity of HeidelbergHeidelbergGermany

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