Imaging technology for myocardial perfusion single-photon emission computed tomography 2018 in Japan
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Recently, nuclear cardiology has dramatically advanced by a new technology development such as the device, short-term acquisition system, image reconstruction algorithm and image analysis. Although these innovations have been gradually employed in routine examinations, we did not investigate the current use of image acquisition, image reconstruction, and image analysis with myocardial perfusion single-photon emission computed tomography (MPS). We investigated the current status of MPS imaging technology in Japan.
We carried out a survey using a Web-based questionnaire system, the opening of which was announced via e-mail, and it was available on a website for 3 months. We collected data on the current use of MPS with 201Tl and/or 99mTc agents with respect to routine protocols, image acquisition, image reconstruction, and image analysis.
We received responses to the Web-based questionnaire from 178 and 174 people for 99mTc and 201Tl MPS, respectively. The routine protocols of MPS of stress-rest and rest-stress MPS on 1-day protocols with 99mTc were 41.2% and 14.5%, respectively, and the rest-only scan response rate was 23.7%, whereas that of 201Tl MPS was 65.9% with stress-rest MPS, 19.0% with rest-only MPS, and 10.9% with stress-rest MPS adding a rest scan 24 h after injection. The filtered back projection (FBP) method is most commonly used image reconstruction method, yielding 70.5% for 99mTc MPS and 76.8% for 201Tl MPS, including combined FBP and ordered subset expectation maximization method. The results for no-correction (NC) images were 49.2% with 99mTc MPS and 55.2% with 201Tl MPS including the response of NC and combined attenuation correction (AC) and scatter correction (SC) (i.e., ACSC) images. The AC or ACSC images of 99mTc and 201Tl were provided by 30–40% of the institutions surveyed.
We investigated the current status of MPS imaging technology in Japan, and found that although the use of various technical developments has been reported, some of these technologies have not been utilized effectively. Hence, we expect that nuclear medicine technology will be used more effectively to improve diagnosis.
KeywordsMyocardial perfusion SPECT Japan Survey Questionnaire Nuclear cardiology technology
The authors wish to thank all participating respondents for their effort in contributing to the surveys. We gratefully acknowledge the support of a JSRT research grant (2017 and 2018).
Compliance with ethical standards
Conflict of interest
H. Ichikawa has received a research grant from JSRT. Other authors report no potential conflicts of interest relevant to this study.
- 3.Society of nuclear medicine. The SNM procedure guideline for general imaging 6.0. https://snmmi.files.cms-plus.com/docs/General_Imaging_Version_6.0.pdf (Reference 2019.7.18)
- 11.Fiechter M, Ghadri JR, Kuest SM, Pazhenkottil AP, Wolfrum M, Nkoulou RN, et al. Nuclear myocardial perfusion imaging with a novel cadmium–zinc–telluride detector SPECT/CT device: first validation versus invasive coronary angiography. Eur J Nucl Med Mol Imaging. 2011;38:2025–30.PubMedCrossRefPubMedCentralGoogle Scholar
- 13.Nkoulou R, Fuchs TA, Pazhenkottil AP, Kuest SM, Ghadri JR, Stehli J, et al. Absolute Myocardial Blood Flow and Flow Reserve Assessed by Gated SPECT with Cadmium–Zinc–Telluride Detectors Using 99mTc-Tetrofosmin: Head-to-Head Comparison with 13N-Ammonia PET. J Nucl Med. 2016;57:1887–922.PubMedCrossRefPubMedCentralGoogle Scholar
- 27.Boucher CA, Zir LM, Beller GA, Okada RD, McKusick KA, Strauss HW, et al. Increased lung uptake of thallium-201 during exercise myocardial imaging: clinical, hemodynamic and angiographic implications in patients with coronary artery disease. Am J Cardiol. 1980;46:189–96.PubMedCrossRefPubMedCentralGoogle Scholar
- 31.Georgoulias P, Tsougos I, Valotassiou V, Tzavara C, Xaplanteris P, Demakopoulos N. Long-term prognostic value of early poststress (99m)Tc-tetrofosmin lung uptake during exercise (SPECT) myocardial perfusion imaging. Eur J Nucl Med Mol Imaging. 2010;37(4):789–98.PubMedCrossRefPubMedCentralGoogle Scholar
- 34.Nakazato R, Tamarappoo BK, Kang X, Wolak A, Kite F, Hayes SW, et al. Quantitative upright-supine high-speed SPECT myocardial perfusion imaging for detection of coronary artery disease: correlation with invasive coronary angiography. J Nucl Med. 2010;51:1724–31.PubMedPubMedCentralCrossRefGoogle Scholar
- 40.Ishihara M, Onoguchi M, Taniguchi Y, Shibutani T. Comparison of conventional and cadmium-zinc-telluride single-photon emission computed tomography for analysis of thallium-201 myocardial perfusion imaging: an exploratory study in normal databases for different ethnicities. Int J Cardiovasc Imaging. 2017;33:2057–66.PubMedCrossRefPubMedCentralGoogle Scholar
- 42.Jinghan Y, Xiyun S, Zuo Z, Da Silva. Iterative SPECT Reconstruction using matched filtering for improved image quality. In: Nuclear science symposium conference IEEE. 2006; p. 2285–2287.Google Scholar
- 43.Vija H, Hawman EG, Engdahl JC. Analysis of a SPECT OSEM reconstruction method with 3D beam modeling and optional attenuation correction: phantom studies. In: 2003 IEEE nuclear science symposium, Medical imaging conference. 2003, Portland, USA, p. 2662–2666.Google Scholar