Imaging findings of mixed connective tissue disease in children and adolescents: a case series
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Mixed connective tissue disease (MCTD) is a rare disease in children and adolescents which overlaps features of juvenile idiopathic arthritis, polymyositis/dermatomyositis, systemic lupus erythematosus, and systemic sclerosis. We have provided an image-based approach for evaluation of MCTD in children and adolescents, outlying the most frequent imaging findings. This approach would aid imagers and clinicians to consider the diagnosis of this rare entity and be able to make an accurate list of differential diagnosis for complex rheumatologic diseases such as MCTD, thus facilitating the ultimate goal of early diagnosis and optimal management of affected children.
KeywordsMixed connective tissue disorder Children and adolescents Differential diagnosis Imaging Juvenile idiopathic arthritis Polymyositis/dermatomyositis Systemic lupus erythematosus Systemic sclerosis
There is no funding used for this study.
Compliance with ethical standards
Conflict of interest
Authors declare that there is no conflict of interest.
This study was approved by the local ethical committee of The Hospital for Sick Children.
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