The safety and efficacy of percutaneous vertebroplasty for patients over 90 years old
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To retrospectively analyze the safety and efficacy of percutaneous vertebroplasty (PVP) for patients aged 90 or over.
Materials and methods
We analyzed 130 consecutive patients with osteoporotic vertebral fractures who underwent a first-time PVP between May 2015 and September 2017 at our institution. We divided them into the elder patient group aged 90 years or over (n = 21) and the younger patient group under 90 years (n = 109). We compared the two groups’ background, treatments, and outcomes using univariate analyzes and the log rank test.
A significant difference was observed in dementia (19% in the younger group vs. 48% in the elder group, p < 0.01). No significant difference was revealed in the procedure time or the rate of complications. The post-PVP mobility function and the pain level were significantly improved compared to before PVP in both groups (p < 0.01 each). No significant differences were observed between the two groups in the recurrence of vertebral fracture after treatment (17% vs. 14%) or the 1-year survival rate (79% vs. 86%), respectively.
The results of our analyzes suggested that a PVP can safely and effectively contribute to pain relief as well as the restoration of ambulation for patients aged 90 or over.
KeywordsVertebroplasty Elderly patient Decubitus position Prophylactic treatment
This work was partly supported by a Grant-in-Aid for Scientific Research of the Japan Society for the Promotion of Science and Grants-in-Aid for Research from the National Center for Global Health and Medicine.
This work was supported in part by Grants-in-Aid for Research from the National Center for Global Health and Medicine (28A5003) and Grants-in-Aid for Scientific Research from Japan society for the promotion of science (16K10333).
Compliance with ethical standards
Conflict of interest
We wish to confirm that there are no known conflicts of interest associated with this publication, and there has been no significant financial support for this work that could have influenced its outcome.
This study was approved by our hospital’s institutional review board, which waived the need for written informed consent from the patients in light of the retrospective study design.
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