Japanese Journal of Radiology

, Volume 35, Issue 12, pp 748–754 | Cite as

A novel utility of 99mTc-GSA SPECT/CT fusion imaging: detection of inadequate portal vein embolization

  • Tatsuaki Sumiyoshi
  • Yasuo Shima
  • Takehiro Okabayashi
  • Yasuhiro Hata
  • Yoshihiro Noda
  • Michihiko Kouno
  • Yuichi Saisaka
  • Kenta Sui
  • Sojiro Morita
  • Yuji Negoro
  • Taijiro Sueda
Original Article
First Online:
Received:
Accepted:
  • 70 Downloads

Abstract

Purpose

Our aim was to determine the utility of Tc-99m-diethylenetriaminepentaacetic acid-galactosyl human serum albumin single-photon-emission computed tomography (99mTc-GSA SPECT/CT) fusion imaging for detecting incomplete portal vein embolization (PVE).

Materials and methods

Fifty-five candidates underwent PVE. Among them, five underwent second PVE. Detectability of first inadequate PVE using CT and 99mTc-GSA SPECT/CT fusion imaging was analyzed.

Results

Cases of inadequate PVE were detected in three patients using CT and in five using 99mTc-GSA SPECT/CT fusion imaging. Fusion imaging detected two cases of insufficient PVE in which portal branches were apparently well embolized on CT. Median value for volumetric rate in the embolized liver was 63.3% after the first PVE and 54.7% after the second (P < 0.01). Median functional rate value in embolized liver was 60.1% after the first PVE and 49.4% after the second (P < 0.01). Median value for change of volumetric and functional rates in embolized liver after the second PVE was 7.1 and 10.3%, respectively, and change of functional rate was greater than that of volumetric rate (P < 0.01).

Conclusions

99mTc-GSA SPECT/CT fusion imaging was useful for detecting inadequate PVE, and second PVE was effective for increasing volumetric and functional rates.

Keywords

99mTc-GSA SPECT/CT fusion imaging Portal vein embolization Extended hepatectomy 
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Notes

Compliance with ethical standards

Funding

We received no financial support.

Conflict of interest

We have no conflict of interest to declare.

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Copyright information

© Japan Radiological Society 2017

Authors and Affiliations

  • Tatsuaki Sumiyoshi
    • 1
  • Yasuo Shima
    • 1
  • Takehiro Okabayashi
    • 1
  • Yasuhiro Hata
    • 2
  • Yoshihiro Noda
    • 2
  • Michihiko Kouno
    • 2
  • Yuichi Saisaka
    • 1
  • Kenta Sui
    • 1
  • Sojiro Morita
    • 2
  • Yuji Negoro
    • 3
  • Taijiro Sueda
    • 4
  1. 1.Department of Gastroenterological SurgeryKochi Health Sciences CenterKochiJapan
  2. 2.Department of RadiologyKochi Health Sciences CenterKochiJapan
  3. 3.Department of Medical OncologyKochi Health Sciences CenterKochiJapan
  4. 4.Department of Surgery, Applied Life Sciences Institute of Biomedical and Health SciencesHiroshima UniversityHiroshimaJapan

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