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Japanese Journal of Radiology

, Volume 35, Issue 10, pp 606–612 | Cite as

MR imaging findings of vertebral involvement in Gorham–Stout disease, generalized lymphatic anomaly, and kaposiform lymphangiomatosis

  • Hiroki KatoEmail author
  • Michio Ozeki
  • Toshiyuki Fukao
  • Masayuki Matsuo
Original Article

Abstract

Purpose

To assess the MR imaging findings of vertebral involvement in Gorham–Stout disease (GSD), generalized lymphatic anomaly (GLA), and kaposiform lymphangiomatosis (KLA).

Methods

Nine patients (three patients with GSD, three with GLA, and three with KLA) who underwent whole-spine MR examinations were included. MR findings of fatty marrow replacement and prolonged T1 and T2 lesions of the vertebrae were retrospectively assessed. Prolonged T1 and T2 lesions were defined as well-defined and round-, oval-, or geographic-shaped areas.

Results

Six patients [one (33%) patient with GSD, two (67%) with GLA, and three (100%) with KLA] showed both fatty marrow replacement and prolonged T1 and T2 lesions. Fatty marrow replacement was seen in the cervical spine of two (33%) patients, thoracic spine of six (100%), lumbar spine of six (100%), and sacral spine of two (33%). Prolonged T1 and T2 lesions were seen in the cervical spine of three (50%) patients, thoracic spine of three (50%), lumbar spine of six (100%), and sacral spine of three (50%).

Conclusion

Both fatty marrow replacement and prolonged T1 and T2 lesions of the vertebrae could be observed in GSD, GLA, and KLA. The most commonly affected site was the lumbar spine, followed by the thoracic spine.

Keywords

Gorham–Stout disease Generalized lymphatic anomaly Kaposiform lymphangiomatosis Vertebra MRI 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Japan Radiological Society 2017

Authors and Affiliations

  • Hiroki Kato
    • 1
    Email author
  • Michio Ozeki
    • 2
  • Toshiyuki Fukao
    • 2
  • Masayuki Matsuo
    • 1
  1. 1.Department of RadiologyGifu University School of MedicineGifuJapan
  2. 2.Department of PediatricsGifu University School of MedicineGifuJapan

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