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Japanese Journal of Radiology

, Volume 33, Issue 8, pp 517–522 | Cite as

Balloon-assisted packing of wide-neck aneurysms with a mixture of n-butyl cyanoacrylate, Lipiodol, and ethanol: an experimental study

  • Fumihiro Tanaka
  • Nobuyuki Kawai
  • Morio SatoEmail author
  • Hiroki Minamiguchi
  • Motoki Nakai
  • Kouhei Nakata
  • Hiroki Sanda
  • Tetsuo Sonomura
Technical Note

Abstract

Purpose

To evaluate the feasibility of balloon-assisted packing with a mixture of n-butyl cyanoacrylate (NBCA), Lipiodol, and ethanol for wide-neck aneurysms.

Materials and methods

Of 10 carotid aneurysms with wide necks created in a swine model, 3 aneurysms (long and short diameters 10.9 × 9.8 mm; neck width 8.3 ± 1.2 mm (mean ± SD)) and 7 aneurysms (11.2 × 9.5 mm; neck width 8.3 ± 1.4 mm) were packed with a mixture of NBCA, Lipiodol, and ethanol in the ratios 1:1:0 (NL11) and 1:1:2 (NLE112), respectively. A microcatheter was advanced into the aneurysm and a balloon catheter was inflated at the aneurysm neck. Ten minutes after injection, the balloon catheter was deflated and its removal was attempted.

Results

For all three aneurysms in the NL11 group, the balloon catheter and the microcatheter adhered strongly to the vessel and could not be adjusted. For all seven aneurysms in the NLE112 group, both the balloon catheter and the microcatheter could be easily removed, which enabled successful full packing of the aneurysm by re-advancing the microcatheter and re-injecting NLE112 after re-inflation of the balloon catheter.

Conclusion

Although at a preliminary stage, balloon-assisted NLE injection is feasible for packing a wide-neck aneurysm.

Keywords

Ethanol n-Butyl cyanoacrylate Lipiodol Balloon-assisted packing Aneurysm 

Notes

Conflict of interest

All the authors declare that they have no conflict of interest.

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Copyright information

© Japan Radiological Society 2015

Authors and Affiliations

  • Fumihiro Tanaka
    • 1
  • Nobuyuki Kawai
    • 1
  • Morio Sato
    • 1
    Email author
  • Hiroki Minamiguchi
    • 1
  • Motoki Nakai
    • 1
  • Kouhei Nakata
    • 1
  • Hiroki Sanda
    • 1
  • Tetsuo Sonomura
    • 1
  1. 1.Department of RadiologyWakayama Medical UniversityWakayamaJapan

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