Feasibility study of a breast density measurement within a direct photon-counting mammography scanner system
To evaluate the clinical feasibility of breast density measurements by a new application within a direct photon-counting mammography scanner system.
Materials and methods
A retrospective study of consecutive women who underwent mammography using a direct photon-counting mammography scanner system (MicroDose mammography SI; Philips Digital Mammography Sweden AB) was performed at the authors’ institution between September and December 2013. Quantitative volumetric glandularity measurements were performed automatically for each acquired mammographic image using an application (Breast Density Measurement; Philips Digital Mammography Sweden AB). The quantitative volumetric glandularity of each breast was defined as the average values for the mediolateral oblique (MLO) and craniocaudal (CC) mammogram views.
Of the 44 women who underwent bilateral mammogram acquisitions, the breast density measurements were performed successfully in 40 patients (90.9 %). A very good to excellent correlation in the quantitative breast density measurements acquired from the MLO and CC images was obtained in the 40 evaluable patients (R = 0.99).
The calculated volumetric glandularity using this new application should correspond well with the true volumetric density of each breast.
KeywordsMammography Breast density measurement Application BI-RADS
- 2.Ursin G, Ma H, Wu AH, Bernstein L, Salane M, Parisky YR, et al. Mammographic density and breast cancer in three ethnic groups. Cancer Epidemiol Biomark Prev. 2003;12:332–8.Google Scholar
- 20.Ducote JL, Molloi S. A quantification of breast density with dual energy mammography: an experimental feasibility study. Med Phys. 2010;37(793–801):24.Google Scholar
- 22.D’Orsi CJ, Vassett JW, Berg WA, Feig SA, Jackson VP, Kopans DB, et al. ACR BI-RADS––mammography. 4th ed. In: ACR breast imaging reporting and data system, breast imaging atlas. Reston: American College of Radiology; 2003.Google Scholar
- 23.Research questions about relationships among variables. In: Dawson B, Trapp RG, editors. Basic and clinical biostatistics, Chapter 8. 4th ed. New York: McGrawHill; 2004. pp. 190–220.Google Scholar
- 24.Venturini E, Losio C, Panizza P, Rodighiero MG, Fedele I, Tacchini S, et al. Tailored breast cancer screening program with microdose mammography, US, and MR imaging: short-term results of a pilot study in 40–49-year-old women. Radiology. 2013;2013(268):347–55. doi:10.1148/radiol.13122278.Epub.CrossRefGoogle Scholar