Japanese Journal of Radiology

, Volume 32, Issue 4, pp 242–250 | Cite as

Guidelines on the use of gelatin sponge particles in embolotherapy

  • Shiro MiyayamaEmail author
  • Koichiro Yamakado
  • Hiroshi Anai
  • Daisuke Abo
  • Tetsuya Minami
  • Haruyuki Takaki
  • Taishi Kodama
  • Takashi Yamanaka
  • Hideyuki Nishiofuku
  • Kengo Morimoto
  • Takeshi Soyama
  • Yu Hasegawa
  • Koichi Nakamura
  • Tomoaki Yamanishi
  • Morio Sato
  • Yasuo Nakajima
Special Report


Gelatin sponge (GS) is one of the most widely used embolic agents in interventional procedures. There are four commercially available GS products in Japan; however, the endovascular use of Gelfoam and Spongel is off-label, and Gelpart can only be used for hepatic artery embolization and Serescue can only be used for hemostasis of arterial bleeding. GS has been used for a variety of clinical indications, mainly tumor embolization and stopping massive arterial bleeding. The optimal size and preparation procedure of GS particles differs slightly for each clinical indication. In addition, there is a risk of ischemic and/or infectious complications associated with GS embolization in various situations. Therefore, radiologists should be familiar with not only the preparation and handling of GS particles, but also the disadvantages and potential risks, in order to perform GS embolization safely and effectively.


Gelatin sponge Endovascular use Embolization Indication Complication 


Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Japan Radiological Society 2014

Authors and Affiliations

  • Shiro Miyayama
    • 1
    Email author
  • Koichiro Yamakado
    • 2
  • Hiroshi Anai
    • 3
  • Daisuke Abo
    • 4
  • Tetsuya Minami
    • 5
  • Haruyuki Takaki
    • 2
  • Taishi Kodama
    • 2
  • Takashi Yamanaka
    • 2
  • Hideyuki Nishiofuku
    • 3
  • Kengo Morimoto
    • 3
  • Takeshi Soyama
    • 4
  • Yu Hasegawa
    • 6
  • Koichi Nakamura
    • 7
  • Tomoaki Yamanishi
    • 8
  • Morio Sato
    • 9
  • Yasuo Nakajima
    • 10
  1. 1.Department of Diagnostic RadiologyFukuiken Saiseikai HospitalFunabashiJapan
  2. 2.Department of Interventional RadiologyMie University School of MedicineTsuJapan
  3. 3.Department of RadiologyNara Medical UniversityKashiharaJapan
  4. 4.Department of RadiologyHokkaido University School of MedicineSapporoJapan
  5. 5.Department of RadiologyKanazawa University School of MedicineKanazawaJapan
  6. 6.Department of Diagnostic RadiologySapporo City General HospitalSapporoJapan
  7. 7.Department of RadiologyNoto General HospitalNanaoJapan
  8. 8.Department of RadiologyKochi University School of MedicineNangokuJapan
  9. 9.Department of RadiologyWakayama Medical UniversityWakayamaJapan
  10. 10.Department of RadiologySt. Marianna University School of MedicineKawasakiJapan

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