Japanese Journal of Radiology

, Volume 30, Issue 4, pp 358–364

Optimal contrast material concentration for distinguishing among carotid artery lumen, carotid stent, and neck in cone-beam computed tomography during carotid angiography: basic and clinical studies

  • Seiki Hosokawa
  • Nobuyuki Kawai
  • Morio Sato
  • Hiroki Minamiguchi
  • Motoki Nakai
  • Tadayoshi Nishioku
  • Tetsuo Sonomura
  • Hiroyuki Matsumoto
  • Osamu Masuo
  • Toru Itakura
Technical note

DOI: 10.1007/s11604-011-0048-1

Cite this article as:
Hosokawa, S., Kawai, N., Sato, M. et al. Jpn J Radiol (2012) 30: 358. doi:10.1007/s11604-011-0048-1

Abstract

Purpose

To explore the optimal contrast material (CM) concentration for distinguishing CM, carotid stent (CS), and neck components in cone-beam computed tomography (CBCT) during carotid angiography (CBCT-CA).

Materials and methods

A neck phantom containing CS and contrast-filled imitation vessels of 9 mm diameter was scanned using CBCT. CM (300 mgI/ml) was used in concentrations of 100, 50, 33, 10, 5, and 1%. In a clinical study, 30 patients with a CS (Precise or Wallstent) underwent CBCT-CA with CM injected at a rate of 3 ml/s and a concentration of 10 or 20%.

Results

In the basic study, CBCTA using 5% CM enabled clear distinction among the three components under windowing at 1500 width and 300 center, and showed the exact diameter of the imitation vessel. Pixel values of CM inside the Precise and the Wallstent were 622.2 ± 32.9 (mean ± SD) and 746.0 ± 27.9, respectively. In the clinical study using CM at concentrations of 10 and 20%, pixel values of CM inside the Wallstent were 632.3 ± 69.2 and 1024.5 ± 99.0, respectively.

Conclusion

Optimal CM concentration for distinguishing among the three components was 5% in the basic study; the optimal concentration was 10% in the clinical study.

Keywords

Carotid stent Carotid artery C-arm computed tomography Contrast material Image quality 

Copyright information

© Japan Radiological Society 2012

Authors and Affiliations

  • Seiki Hosokawa
    • 1
  • Nobuyuki Kawai
    • 1
  • Morio Sato
    • 1
  • Hiroki Minamiguchi
    • 1
  • Motoki Nakai
    • 1
  • Tadayoshi Nishioku
    • 1
  • Tetsuo Sonomura
    • 1
  • Hiroyuki Matsumoto
    • 2
  • Osamu Masuo
    • 2
  • Toru Itakura
    • 2
  1. 1.Department of RadiologyWakayama Medical UniversityWakayamaJapan
  2. 2.Department of NeurosurgeryWakayama Medical UniversityWakayamaJapan

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