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Radiation Medicine

, 26:151 | Cite as

Discordance of motion artifacts on magnetic resonance imaging in Creutzfeldt-Jakob disease: comparison of diffusion-weighted and conventional imaging sequences

  • Taro Shimono
  • Takahiro Tsuboyama
  • Masatomo Kuwabara
  • Sung-woon Im
  • Yukinobu Yagyu
  • Izumi Imaoka
  • Ryuichiro Ashikaga
  • Makoto Hosono
  • Takamichi Murakami
Original Article

Abstract

Purpose

Motion artifact is problematic in the diagnosis of Creutzfeldt-Jakob disease (CJD) because of dementia. The purpose was to compare the occurrence of this artifact between a diffusion-weighted (DW) magnetic resonance (MR) imaging sequence and conventional sequences.

Materials and methods

Ten MR examinations comprising T2-weighted, T1-weighted, DW, and fluid-attenuated inversion recovery imaging in seven CJD patients were retrospectively evaluated. The occurrence of motion artifacts on each sequence were assessed, and the examination was classified into four groups as follows: group A, motion artifact not revealed on DW imaging but revealed on one or more other sequences; group B, revealed on DW imaging and one or more other sequences; group C, not revealed on any sequences; and group D, revealed on DW imaging but not on any other sequences.

Results

The 10 MR examinations were classified as eight group A (80%), one B (10%), one C (10%), and zero D (0%).

Conclusion

Motion artifacts are likely to occur in any conventional imaging sequences in CJD, but the fast-imaging ability of DW imaging can reduce this artifact. The combination of an absence of motion artifact on DW imaging and the presence on conventional sequences may be one of the frequent findings of CJD.

Key words

Creutzfeldt-Jakob disease Magnetic resonance imaging Diffusion-weighted imaging 

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Copyright information

© Japan Radiological Society 2008

Authors and Affiliations

  • Taro Shimono
    • 1
  • Takahiro Tsuboyama
    • 1
  • Masatomo Kuwabara
    • 1
  • Sung-woon Im
    • 1
  • Yukinobu Yagyu
    • 1
  • Izumi Imaoka
    • 1
  • Ryuichiro Ashikaga
    • 1
  • Makoto Hosono
    • 1
  • Takamichi Murakami
    • 1
  1. 1.Department of RadiologyKinki University School of MedicineOsaka-SayamaJapan

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