Sliding thin slab, minimum intensity projection imaging for objective analysis of emphysema
ORIGINAL ARTICLE
Received:
Accepted:
- 62 Downloads
- 10 Citations
Abstract
Purpose
The aim of this study was to determine whether sliding thin slab, minimum intensity projection (STS-MinIP) imaging is more advantageous than thin-section computed tomography (CT) for detecting and assessing emphysema.
Materials and methods
Objective quantification of emphysema by STS-MinIP and thin-section CT was defined as the percentage of area lower than the threshold in the lung section at the level of the aortic arch, tracheal carina, and 5 cm below the carina. Quantitative analysis in 100 subjects was performed and compared with pulmonary function test results.
Results
The ratio of the low attenuation area in the lung measured by STS-MinIP was significantly higher than that found by thin-section CT (P < 0.01). The difference between STS-MinIP and thin-section CT was statistically evident even for mild emphysema and increased depending on whether the low attenuation in the lung increased. Moreover, STS-MinIP showed a stronger regression relation with pulmonary function results than did thin-section CT (P < 0.01).
Conclusion
STS-MinIP can be recommended as a new morphometric method for detecting and assessing the severity of emphysema.
Key words
Computed tomography (CT) Minimum intensity projection Emphysema Pulmonary Lung FunctionPreview
Unable to display preview. Download preview PDF.
References
- 1.Pauwell, RA, Buist, AS, Calverley, PMA, Jenkins, CR, Hurd, SS 2001Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary diseaseAm J Respir Crit Care Med163125676Google Scholar
- 2.Murray, CJL, Lopez, AD 1996Evidence-based health policy—lessons from the Global Burden of Disease StudyScience2747403PubMedCrossRefGoogle Scholar
- 3.Niewoehner, DE, Kleinerman, J, Rice, DB 1974Pathologic changes in the peripheral airways of young cigarette smokersN Engl J Med2917558PubMedCrossRefGoogle Scholar
- 4.Gevenois, PA, de Maertelaer, V, De Vuyst, P, Zanen, J, Ternault, JC 1995Comparison of computed density and macroscopic morphometry in pulmonary emphysemaAm J Respir Crit Care Med1526537PubMedGoogle Scholar
- 5.Gevenois, PA, de Vuyst, P, De Maertelaer, V, Zanen, J, Jacobovitz, D, Cosio, MG, et al. 1996Comparison of computed density and microscopic morphometry in pulmonary emphysemaAm J Respir Crit Care Med15418792PubMedGoogle Scholar
- 6.Miller, RR, Müller, NL, Vedal, S, Morrison, NJ, Staples, CA 1989Limitations of computed tomography in the assessment of emphysemaAm Rev Respir Dis1399803PubMedGoogle Scholar
- 7.Mergo, PJ, Williams, WF, Gonzalez-Rothi, R, Gibson, R, Ros, PR, Staab, EV, et al. 1998Three-dimensional volumetric assessment of abnormally low attenuation of the lung from routine helical CT: inspiratory and expiratory quantificationAJR Am J Roentgenol170135560PubMedGoogle Scholar
- 8.Park, KJ, Bergin, CJ, Clausen, JL 1999Quantitation of emphysema with three-dimensional CT densitometry: comparison with two-dimensional analysis, visual emphysema scores, and pulmonary function test resultsRadiology2115417PubMedGoogle Scholar
- 9.Arakawa, A, Yamashita, Y, Nakayama, Y, Kadota, M, Korogi, H, Kawano, O, et al. 2001Assessment of lung volumes in pulmonary emphysema using multidetector helical CT: comparison with pulmonary function testsComput Med Imaging Graphics25399404CrossRefGoogle Scholar
- 10.Remy-Jardin, M, Remy, J, Gosselin, B, Copin, MC, Wurtz, A, Duhamel, A 1996Sliding thin slab, minimum intensity projection technique in the diagnosis of emphysema: histopathologic-CT correlationRadiology20066571PubMedGoogle Scholar
- 11.American Thoracic Society1987Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthmaAm Rev Respir Dis1362254Google Scholar
- 12.Sweatman, MC, Millar, AB, Strickland, B, Turner-Warwick, M 1990Computed tomography in adult obliterative bronchiolitisClin Radiol411169PubMedCrossRefGoogle Scholar
- 13.Turton, CW, Williams, G, Green, M 1981Cryptogenic obliterative bronchiolitis in adultsThorax3680510PubMedCrossRefGoogle Scholar
- 14.Nakano, Y, Sakai, H, Muro, S, Hirai, T, Oku, Y, Nishimura, K, et al. 1999Comparison of low attenuation areas on computed tomographic scans between inner and outer segments of the lung in patients with chronic obstructive pulmonary disease: incidence and contribution to lung functionThorax543849PubMedCrossRefGoogle Scholar
- 15.Sakai, N, Mishima, M, Nishimura, K, Itoh, H, Kuno, K 1994An automated method to assess the distribution of low attenuation areas on chest CT scans in chronic pulmonary emphysema patientsChest106131925PubMedGoogle Scholar
- 16.Napel, S, Rubin, GD, Jeffrey, RB,Jr 1993STS-MIP: a new reconstruction technique for CT of the chestJ Comput Assist Tomogr178328PubMedGoogle Scholar
- 17.Bankier, AA, Maertelaer, VD, Keyzer, C, Gevenois, PA 1999Pulmonary emphysema: subjective visual grading versus objective quantification with macroscopic morphometry and thin-section CT densitometryRadiology2118518PubMedGoogle Scholar
- 18.Bergin, C, Müller, N, Nichols, DM, Lillington, G, Hogg, JC, Mullen, B, et al. 1986The diagnosis of emphysema: a computed tomographic-pathologic correlationAm Rev Respir Dis1335416PubMedGoogle Scholar
- 19.Wittram, C, Batt, J, Rappaport, DC, Hutcheon, MA 2002Inspiratory and expiratory helical CT of normal adults: comparison of thin section scans and minimum intensity projection imagesJ Thorac Imaging74752CrossRefGoogle Scholar
- 20.Knudson, RJ, Standen, JR, Kaltenborn, WT, Kundson, DE, Rehm, K, Habib, MP, et al. 1991Expiratory computed tomography for assessment of suspected pulmonary emphysemaChest99135766PubMedGoogle Scholar
- 21.Paranjpe, DV, Bergin, CJ 1994Spiral CT of the lungs: optimal technique and resolution compared with conventional CTAJR Am J Roentgenol1625617PubMedGoogle Scholar
Copyright information
© Japan Radiological Society 2006