Epidemiological features of allergic rhinitis in four major cities in Western China

  • Ji Shen (申 迹)
  • Xia Ke (柯 霞)
  • Suling Hong (洪苏玲)
  • Qing Zeng (曾庆)
  • Chuanyu Liang (梁传余)
  • Tongying Li (李同英)
  • Anzhou Tang (唐安洲)


Allergic rhinitis (AR), with an increasing uptrend of the prevalence in many developed and developing countries, is a global health problem that affects people of all ages and ethnic groups. However, data on the prevalence of self-reported AR in western China are rare. This study investigated the epidemiological features of self-reported AR in western China. In the cross-sectional, population-based study, a validated questionnaire survey on self-reported AR was carried out in 4 major cities in western China by multistage, stratified and cluster sampling, from January to December 2008. The total prevalence rate was 34.3%, with 32.3% (Chongqing), 34.3% (Chengdu), 37.9% (Urumqi), 30.3% (Nanning), respectively. The prevalence presented to increase with age before 30 years old while decrease with age after 30 years old, and the highest prevalence was in 19–30 years group in Chongqing, Chengdu and Nanning which significantly showed “persistent and moderate-severe” type (P<0.0001); In Urumqi, there wasn’t a significant increasing or decreasing trend of prevalence rate with age but with an “intermittent and mild”predominance (P<0.0001). There were no distinct sexual differences in prevalence rates in the 4 cities. The morbidity was positively related to monthly average temperature and sunshine (r=0.76645, P=0.0036; r=0.67303, P=0.0165), but negatively associated with relative humidity (r=−0.64391, P=0.0238) in Urumqi. Interestingly, the monthly morbidity was negatively associate with average temperature, sunshine and precipitation in Nanning (r=−0.81997, P=0.0011; r=−0.60787, P=0.0360; r=−0.59443, P=0.0415). Self-reported AR is becoming common in western China with a rapid development in recent years, affecting about three persons out of ten. The climatic factors may have an indirect impact on the prevalence rate through the effects on the local allergens.

Key words

western China epidemiology intermittent allergic rhinitis persistent allergic rhinitis self-reported allergic rhinitis 


  1. 1.
    Bousquet J, van Cauwenberge P, Khaltaev N, et al. Aria Workshop Group, World Health Organization: Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol, 2001,108(Suppl 5):S147–S334PubMedCrossRefGoogle Scholar
  2. 2.
    Ciprandi G, Vizzaccaro A, Cirillo I, et al. Increase of asthma and allergic rhinitis prevalence in young Italian men. Int Arch Allergy Immunol, 1996,111(279–283): 278–28PubMedGoogle Scholar
  3. 3.
    Asher MI, Montefort S, Björkstén B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet, 2006,368(9537):733–743. Erratum in: Lancet, 2007,370(9593):1128PubMedCrossRefGoogle Scholar
  4. 4.
    Bellanti JA, Wallerstedt, DB. Allergic rhinitis update: Epidemiology and natural history. Allergy Asthma Proc, 2000,21(6):367–370PubMedCrossRefGoogle Scholar
  5. 5.
    Bousquet J, Khaltaev N, Cruz AA, et al. Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2) LEN and AllerGen). Allergy, 2008,63(Suppl 86):8–160PubMedCrossRefGoogle Scholar
  6. 6.
    Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Lancet, 1998,351(9111):1225–1232CrossRefGoogle Scholar
  7. 7.
    Burney PG, Luczynska C, Chinn S, et al. The european Community Respiratory Health Survey. Eur Respir J, 1994,7(5):954–960PubMedCrossRefGoogle Scholar
  8. 8.
    Naing L, Winn T, Rusli BN. Practical issues in calculating the sample size for prevalence studies. Arch Orofac Sci, 2006,1(1):9–14Google Scholar
  9. 9.
    Humphry RW, Cameron A, Gunn GJ. A practical approach to calculate sample size for herd prevalence surveys. Prev Vet Med, 2004,65(3–4):173–188PubMedCrossRefGoogle Scholar
  10. 10.
    Zhao T, Wang A, Chen Y, et al. Prevalence of childhood asthma, allergic rhinitis and eczema in Urumqi and Beijing. J Paediatr Child Health, 2000,36(2):128–133PubMedCrossRefGoogle Scholar
  11. 11.
    Lee YL, Shaw CK, Su HJ, et al. Climate, traffic-related air pollutants and allergic rhinitis prevalence in middle-school children in Taiwan. Eur Respir J, 2003,21(6): 964–970PubMedCrossRefGoogle Scholar
  12. 12.
    Zhao T, Wang HJ, Chen Y, et al. Prevalence of childhood asthma, allergic rhinitis and eczema in Urumqi and Beijing. J Paediatr Child Health, 2000,36(2):128–133PubMedCrossRefGoogle Scholar
  13. 13.
    Leung R, Ho P. Asthma, allergy, and atopy in three south-east Asian populations. Thorax, 1994,49(12):1205–1210PubMedCrossRefGoogle Scholar
  14. 14.
    Zhang L, Han D, Huang D, et al. Prevalence of self-reported allergic rhinitis in eleven major cities in China. Int Arch Allergy Immunol, 2008,149(1):47–57PubMedCrossRefGoogle Scholar
  15. 15.
    Bauchau V, Durham SR. Prevalence and rate of diagnosis of allergic rhinitis in Europe. Eur Respir J, 2004,24(5): 758–764PubMedCrossRefGoogle Scholar
  16. 16.
    Law M, Morris JK, Wald N, et al. Changes in atopy over a quarter of a century, based on cross sectional data at three time periods. BMJ, 2005,330(7501):1187–1188PubMedCrossRefGoogle Scholar
  17. 17.
    Broder I, Higgins MW, Mathews KP, et al. Epidemiology of asthma and allergic rhinitis in a total community, Tecumseh, Michigan. III. Second survey of the community. J Allergy Clin Immunol, 1974,53(3):127–138PubMedCrossRefGoogle Scholar
  18. 18.
    Schachter J, Higgins MW. Median age at onset of asthma and allergic rhinitis in Tecumseh, Michigan. J Allergy Clin Immunol, 1976,57(4):342–351PubMedCrossRefGoogle Scholar
  19. 19.
    Droste JHJ, Kerkhof M, De Monchy JGR, et al. Association of skin test reactivity, specific IgE, total IgE, and eosinophils with nasal symptoms in a community-based population study. J Allergy Clin Immunol, 1996,97(4): 922–932PubMedCrossRefGoogle Scholar
  20. 20.
    Vignola AM, Scichilone N, Bousquet J, et al. Aging and asthma: pathophysiological mechanisms. Allergy, 2003, 58(3):165–175PubMedCrossRefGoogle Scholar
  21. 21.
    Huss K, Naumann PL, Mason PJ, et al. Asthma severity, atopic status, allergen exposure, and quality of life in elderly persons. Ann Allergy Asthma Immunol, 2001,86(5): 524–530PubMedCrossRefGoogle Scholar
  22. 22.
    Qian D, Hong SL. Prevalence of allergens for Chongqing patients with allergic rhinitis. J Chongqing Med Univ (Chinese), 2008,33(5):531–535Google Scholar
  23. 23.
    Meng J, Yin R, Zhang H. Investigation of skin prick test in Chengdu patients with allergic rhinitis. West China Med J (Chinese), 2009,24(3):567–570Google Scholar
  24. 24.
    Lu Q, Liang J, Liu B, et al. Common allergens analysis in patients with perennial allergic rhinitis in Nanning. Guangxi Med J (Chinese), 2007,29(10):1492–1494Google Scholar
  25. 25.
    Janson C, Anto J, Burney P, et al. The European Community Respiratory Health Survey: what are the main results so far? European Community Respiratory Health Survey II. Eur Respir J, 2001,18(3):598–611PubMedCrossRefGoogle Scholar
  26. 26.
    Demoly P, Allaert FA, Lecasble M, et al. Validation of the classification of ARIA (allergic rhinitis and its impact on asthma). Allergy, 2003,58(7):672–675PubMedCrossRefGoogle Scholar
  27. 27.
    Wang H, Xiang Y, Chen X, et al. Investigation of allergens in patients with asthma and allergic rhinitis in Xinjiang. J Xinjiang Med Univ (Chinese), 2007,30(10): 1086–1088Google Scholar
  28. 28.
    Chavarria JF. Asthma admissions and weather conditions in Costa Rica. Arch Dis Child, 2001,84(6):514–515PubMedCrossRefGoogle Scholar
  29. 29.
    Khot A, Burn R, Evans N, et al. Biometeorological triggers in childhood asthma. Clin Allergy, 1988,18(4):351–358PubMedCrossRefGoogle Scholar
  30. 30.
    Ehara A, Takasaki H, Takeda Y, et al. Are high barometric pressure, low humidity and diurnal change of temperature related to the onset of asthmatic symptoms? Pediatr Int, 2000,42(3):272–274PubMedCrossRefGoogle Scholar
  31. 31.
    Hashimoto M, Fukuda T, Shimizu T, et al. Influence of climate factors on emergency visits for childhood asthma attack. Pediatr Int, 2004,46(1):48–52PubMedCrossRefGoogle Scholar
  32. 32.
    Jones AM, Harrison RM. The effects of meteorological factors on atmospheric bioaerosol concentrations — a review. Sci Total Environ, 2004,326(1–3):151–180PubMedGoogle Scholar
  33. 33.
    Burge HA. An update on pollen and fungal spore aerobiology. J Allergy Clin Immunol, 2002,110(4):544–552PubMedCrossRefGoogle Scholar

Copyright information

© Huazhong University of Science and Technology and Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Ji Shen (申 迹)
    • 1
  • Xia Ke (柯 霞)
    • 2
  • Suling Hong (洪苏玲)
    • 2
  • Qing Zeng (曾庆)
    • 3
  • Chuanyu Liang (梁传余)
    • 4
  • Tongying Li (李同英)
    • 5
  • Anzhou Tang (唐安洲)
    • 6
  1. 1.Department of Otorhinolaryngology-Head and Neck SurgeryThe People’s Hospital of ChangshouChongqingChina
  2. 2.Department of Otorhinolaryngology-Head and Neck SurgeryThe First Affiliated Hospital of Chongqing Medical UniversityChongqingChina
  3. 3.Department of Epidemiology and Hygienic StatisticsChongqing Medical UniversityChongqingChina
  4. 4.Department of Otorhinolaryngology-Head and Neck SurgeryWest China Hospital of Sichuan UniversityChengduChina
  5. 5.Department of Otorhinolaryngology-Head and Neck SurgeryThe First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina
  6. 6.Department of Otorhinolaryngology-Head and Neck SurgeryThe First Affiliated Hospital of Guangxi Medical UniversityNanningChina

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