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Comparative study on 16-slice CT coronary angiography vs conventional coronary angiography—A report of 38 cases

  • Yan Chen (陈 艳)
  • Ping Han (韩 萍)
  • Bo Liang (梁 波)
  • Huimin Liang (梁惠民)
  • Ziqiao Lei (雷子乔)
  • Zhiliang Tian (田志梁)
  • Gansheng Feng (冯敢生)
  • Jie Xiao (肖 杰)
Article

Summary

The clinical application of 16-slice CT coronary angiography (CTCA) and the impact of plaques differently characterized on assessing coronary artery stenosis were evaluated. Thirty-eight patients with coronary artery disease diagnosed by conventional coronary angiography (CAG) underwent 16-slice CTCA (collimation: 16×0.75 mm; rotation time: 420 msec; kernel: 35f; effective current: 500 mAs; tube voltage: 120 kV). The interval between CTCA and CAG was within one month. CTCA was evaluated by consensus of two independent experienced radiologists unknowing CAG findings. Original images, maximum intensity projections and multiplanar reconstructions were used to assess coronary artery stenosis. For a determined plaque an attenuation value ⩾130 HU was considered as calcified, and <130 HU noncalcified. The plaques were then classified into significant calcification (extensive calcification), medium calcification (small isolated calcification) and noncalcification. The diagnostic accuracy of 16-slice CTCA findings as well as to detect ⩾50% stenoses caused by plaques was evaluated respectively regarding CAG as the standard of reference. In comparison with CAG findings, the sensitivity, specificity, positive and negative predictive value derived from CTCA for mild stenosis (<50%) were 72.7%, 38.5%, 50%, 62.5%, respectively; for moderate stenosis (50%–75%) 82.4%, 72.7%, 70%, 84.2%, resepctively; and for severe coronary stenosis (>75%) 85%, 90.5%, 81%, 92.7% respectively. With the increase of stenoses degree, the value of CTCA was greater. For the classification of the plaque calcification with ⩾50% stenosis CTCA attained the sensitivity, specificity, positive and negative predictive value for severe calcificatoin 73.3%, 22.2%, 61.1% and 33.3%, respectively; for moderate calcification 70%, 55.6%, 63.6% and 62.5%, respectively; for noncalcification 93.8%, 85.7%, 93.8% and 85.7% respectively. CTCA was restricted in assessing coronary artery stenosis in the presence of calcification, but CTCA value was much improved in assessing non-calcified stenosis. It was concluded that 16-slice CTCA could provide useful information about coronary artery stenosis, especially for severe stenosis (⩾50%) and non-calcified plaque. Since CTCA is a noninvasive technique, it may be useful in screening coronary artery disease.

Key words

X-ray computed, tomography coronary artery disease angiocardiography 

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References

  1. 1.
    Nieman K, Oudkerk M, Rensing B J et al. Coronary angiography with multi-slice computed tomography. Lancet, 2001,357(9256):599–603PubMedCrossRefGoogle Scholar
  2. 2.
    Giesler T, Baum U, Ropers D et al. Noninvasive visualization of coronary arteries using contrastenhanced multidetector CT: influence of heart rate on image quality and stenosis detection. AJR, 2002,179(4):911–916PubMedGoogle Scholar
  3. 3.
    Nieman K, Cademartiri F, Lemos P A et al. Reliable noninvasive coronary angiography with fast submillimeter multislice spiral computed tomography. Circulation, 2002,106(16):2051–2054PubMedCrossRefGoogle Scholar
  4. 4.
    Achenbach S, Giesler T, Ropers D et al. Detection of coronary artery stenoses by contrast-enhanced, retrospectively electrocardiographically gated, multislice spiral computed tomography. Circulation, 2001,103(21):2535–2538PubMedGoogle Scholar
  5. 5.
    Nieman K, Rensing B J, van Geuns R J M et al. Non-invasive coronary angiography with multislice spiral CT: the impact of heart rate. Heart, 2002,88(5):470–474PubMedCrossRefGoogle Scholar
  6. 6.
    Flohr T, Ohnesorge B. Heart rate adaptive optimization of spatial and temporal resolution for electrocardiogram-gated multislice spiral CT of the heart. J Comput Assist Tomogr, 2001,25(6):907–923PubMedCrossRefGoogle Scholar
  7. 7.
    Wang Z, Yang Z, Zhu H et al. Detection of coronary artery stenoses using 16-slice spiral CT: comparison with quantitative coronary angiography. J Comput Tomogr, 2003,3(1):7–11Google Scholar
  8. 8.
    Becker C R, Ohnesorge B M, Schoepf U J et al. Current development of cardiac imaging with multidetector row CT. Eur J Radiol, 2000,36(2):97–103PubMedCrossRefGoogle Scholar
  9. 9.
    Schroeder S, Kopp A F, Baumbach A et al. Noninvasive detection and evaluation of atherosclerotic coronary plaque with multislice computed tomography. J Am Coll Cardiol, 2001,37(5):1430–1435PubMedCrossRefGoogle Scholar

Copyright information

© Huazhong University of Science and Technology 2008

Authors and Affiliations

  • Yan Chen (陈 艳)
    • 1
  • Ping Han (韩 萍)
    • 1
  • Bo Liang (梁 波)
    • 1
  • Huimin Liang (梁惠民)
    • 1
  • Ziqiao Lei (雷子乔)
    • 1
  • Zhiliang Tian (田志梁)
    • 1
  • Gansheng Feng (冯敢生)
    • 1
  • Jie Xiao (肖 杰)
    • 1
  1. 1.Department of Radiology, Union Hospital, Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

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