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Ionics

, Volume 25, Issue 11, pp 5537–5550 | Cite as

Simultaneous detection of glutathione, threonine, and glycine at electrodeposited RuHCF/rGO–modified electrode

  • Saranya S
  • Jency Feminus J
  • Geetha B
  • Deepa P NEmail author
Original Paper
  • 54 Downloads

Abstract

Ruthenium hexacyanoferrate/reduced graphene oxide (RuHCF/rGO) electrode was fabricated by electrochemical deposition of RuHCF on a rGO-modified electrode. Electrocatalytic oxidation and determination of glutathione, threonine, and glycine were carried out simultaneously using the modified electrode. The electrochemical sensor showed a wide linear response in the concentration range of 5.12–25.58 μM for glutathione, 1.98–15.86 μM for threonine, and 1.25–7.49 μM for glycine. The RuHCF/rGO–modified electrode showed minimal interference in the presence of related compounds. The limit of detection observed for glutathione, threonine, and glycine was 1.70, 0.66, and 0.4 μM respectively. Saliva samples were used for checking the analytical utility of the RuHCF/rGO–modified electrode for sensing the three analytes, and the recovery percentages were between 95.80 and 98.03. The electrode also exhibited long-term stability and shelf life.

Keywords

Electrochemical Ruthenium hexacyanoferrate Reduced graphene oxide Glutathione Threonine Glycine 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Analytical ChemistryUniversity of MadrasChennaiIndia

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