Ionics

, Volume 21, Issue 2, pp 547–555 | Cite as

Highly sensing graphene oxide/poly-arginine-modified electrode for the simultaneous electrochemical determination of buspirone, isoniazid and pyrazinamide drugs

  • Balamurugan Devadas
  • Srikanth Cheemalapati
  • Shen-Ming Chen
  • M. Ajmal Ali
  • Fahad M. A. Al-Hemaid
Original Paper
First Online:
Received:
Revised:
Accepted:

Abstract

For the first time, an electrochemical method was proposed for the simultaneous determination of isoniazid (INZ), pyrazinamide (PYZ) and buspirone HCl (BPH) at graphene oxide (GO)/poly-l-arginine (PAG)-modified glassy carbon electrode (GCE). The GO was synthesized by modified Hummer’s method and the surface morphologies of GO and PAG were characterized by scanning electron microscopy (SEM). The simultaneous determinations of INZ, PYZ and BPH were determined by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. The proposed GO/PAG/GCE sensor has a wide linear range of 20 to 1,400 μM for INZ, 25 to 900 μM for BPH and 25 to 1,600 μM for PYZ, respectively. The low limit of detection (LOD) values was found as 2.59, 3.54 and 3.28 μM respectively, for INZ, BPH and PYZ. The practicality and applicability of the proposed electrode was demonstrated in blood serum and commercially available pharmaceutical tablets. In addition, the obtained results for pharmaceutical tablets were in good agreement with the label claim of the tablets and the proposed method could be employed in pharmaceutical laboratories in the near future.

Keywords

Graphene oxide Arginine Isoniazid Pyrazinamide Buspirone 

Notes

Acknowledgments

Research supported by the King Saud University, Deanship of Scientific Research, College of Science, Research Center, Saudi Arabia.

References

  1. 1.
    Geim AK (2009) Science 324:1530CrossRefGoogle Scholar
  2. 2.
    Novoselov KS, Falko VI, Colombo L, Gellert PR, Schwab MG, Kim K (2012) Nature 490:192CrossRefGoogle Scholar
  3. 3.
    Novoselov KS, Geim AK, Morozov SV, Jiang D, Zhang Y, Dubonos SV, Grigorieva IV, Firsov AA (2004) Science 306:666CrossRefGoogle Scholar
  4. 4.
    Pumera M, Ambrosi A, Bonanni A, Chng ELK, Poh HL (2010) Trends Anal Chem 29:954CrossRefGoogle Scholar
  5. 5.
    Choi W, Lahiri I, Seelaboyina R, Kang YS (2010) Crit Rev Solid State Mater Sci 35:52CrossRefGoogle Scholar
  6. 6.
    Hummers WS, Offeman RE (1958) J Am Chem Soc 80:1339CrossRefGoogle Scholar
  7. 7.
    Mani V, Devadas B, Chen SM (2013) Biosens Bioelectron 41:309CrossRefGoogle Scholar
  8. 8.
    Chung C, Kim YK, Shin D, Ryoo SR, Hong BH (2013) Acc Chem Res 46:2211CrossRefGoogle Scholar
  9. 9.
    Thangamuthu R, Pan YC, Chen SM (2010) Electroanalysis 22:1812CrossRefGoogle Scholar
  10. 10.
    Cheemalapati S, Palanisamy S, Chen SM (2014) J Appl Electrochem 44:317CrossRefGoogle Scholar
  11. 11.
    Santos DP, Bergamini MF, Fogg AG, Zanoni MVB (2005) Microchim Acta 151:127CrossRefGoogle Scholar
  12. 12.
    Wei M, Ming SD (2007) Chin J Anal Chem 35:66CrossRefGoogle Scholar
  13. 13.
    Zhang K, Luo P, Wu JJ, Wang W, Ye B (2013) Anal Methods 5:5044CrossRefGoogle Scholar
  14. 14.
    Zhang F, Gu S, Ding Y, Zhou L, Zhang Z, Li L (2013) J Electroanal Chem 698:25CrossRefGoogle Scholar
  15. 15.
    Abedin Khan MDJ, Ahmed Z (2013) Int J Gen Med Pharm 2:2319Google Scholar
  16. 16.
    Yan X, Bo X, Guo L (2011) Sensors Actuators B 155:837CrossRefGoogle Scholar
  17. 17.
    Nagaraja P, Murthy KCS, Yathirajan HS (1996) Talanta 43:1075CrossRefGoogle Scholar
  18. 18.
    Khuhawar MY, Rind FMA (2002) J Chromatogr B 766:357CrossRefGoogle Scholar
  19. 19.
    Parfitt K, Sweetman SC, Blake PS, Parsons AV (1999) Martindale - The extra pharmacopoeia, 32nd edn. Pharmaceutical Press, London, pp 643–644Google Scholar
  20. 20.
    Dommisse CS, De Vane CL (1985) Intell Clin Pharmacol 19:624Google Scholar
  21. 21.
    Gannu R, Yamsani SK, Palem CR, Yamsani VV, Kotagiri H (2009) Anal Chim Acta 647:226CrossRefGoogle Scholar
  22. 22.
    Jaisuresh K (2013) Nephrology 2013:3Google Scholar
  23. 23.
    Hest RV, Baars H, Kik S, Gerven PV, Trompenaars MC, Kalisvaart N, Keizer S, Borgdorff M, Mensen M, Cobelens F (2004) Clin Infect Dis 39:488CrossRefGoogle Scholar
  24. 24.
    Tafazoli S, Mashregi M, O’Brien PJ (2008) Toxicol Appl Pharmacol 229:94CrossRefGoogle Scholar
  25. 25.
    Takka S, Sakr A, Goldberg A (2003) J Control Release 88:147CrossRefGoogle Scholar
  26. 26.
    Oliveira PRD, Oliveira MM, Zarbin JGA, Marcolino-Junior LH, Bergamini MF (2012) Sensors Actuators B 171-172:795CrossRefGoogle Scholar
  27. 27.
    Safavi A, Karimi MA, Nezhad MRH, Kamali R, Saghir N (2004) Spectrochim Acta A 60:765CrossRefGoogle Scholar
  28. 28.
    Wu B, Wang Z, Xue Z, Zhou X, Du J, Liu X, Lu X (2012) Analyst 137:3644CrossRefGoogle Scholar
  29. 29.
    Cheemalapati S, Palanisamy S, Chen SM (2013) Int J Electrochem Sci 8:3953Google Scholar
  30. 30.
    Chaitanya AK, Saravanan RS, Jeevanantham S, Vignesh R, Karthik P (2012) Adv Pharmacoepidemiol Drug Saf 1–108:1Google Scholar
  31. 31.
    Madan J, Dwivedi AK, Singh S (2005) Anal Chim Acta 538:345CrossRefGoogle Scholar
  32. 32.
    Faria AF, Souza MVN, Bruns RE, Oliveira MAL (2010) Talanta 82:333CrossRefGoogle Scholar
  33. 33.
    Gong Z, Basir Y, Chu D, Tipton MM (2009) J Chromatogr B 877:1698CrossRefGoogle Scholar
  34. 34.
    Maher HM, Youssef RM (2008) Chemom Intell Lab Syst 94:95CrossRefGoogle Scholar
  35. 35.
    Bergamini MF, Santos DP, Zanoni MVB (2013) J Electroanal Chem 690:47CrossRefGoogle Scholar
  36. 36.
    Foroutan SM, Zarghi A, Shafaati AR, Khoddam A (2004) IL Farmacol 59:739CrossRefGoogle Scholar
  37. 37.
    Jain R, Rani S, Goyal RN (1981) Electrochim Acta 26:1519CrossRefGoogle Scholar
  38. 38.
    Riekes MK, Pereira RN, Rauber GS, Cuffini SL, Campos CEM, Silva MAS, Stulzer HK (2012) J Pharm Biomed Anal 70:188CrossRefGoogle Scholar
  39. 39.
    Chen SZ, Xu F, Zhang H, Zhang ZQ (1993) Talanta 40:1551CrossRefGoogle Scholar
  40. 40.
    Dreyer DR, Park S, Bielawski CW, Ruoff RS (2010) Chem Soc Rev 39:228CrossRefGoogle Scholar
  41. 41.
    Li Y, Ye Z, Zhou J, Liu J, Song G, Zhang K, Ye B (2012) J Electroanal Chem 687:51CrossRefGoogle Scholar
  42. 42.
    Jiang C, Yang T, Jiao K, Gao H (2008) Electrochim Acta 53:2917CrossRefGoogle Scholar
  43. 43.
    Cheemalapati S, Palanisamy S, Mani V, Chen SM (2013) Talanta 117:297CrossRefGoogle Scholar
  44. 44.
    Johnsson K, Schultz PG (1994) J Am Chem Soc 116:7425CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Balamurugan Devadas
    • 1
  • Srikanth Cheemalapati
    • 1
  • Shen-Ming Chen
    • 1
  • M. Ajmal Ali
    • 2
  • Fahad M. A. Al-Hemaid
    • 2
  1. 1.Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and BiotechnologyNational Taipei University of TechnologyTaipeiRepublic of China
  2. 2.Department of Botany and MicrobiologyCollege of Science, King Saud UniversityRiyadhSaudi Arabia

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