Der Nephrologe

, Volume 7, Issue 1, pp 48–51

Akute antikörpervermittelte Rejektion nach Nierentransplantation

Verminderte Inzidenz bei hochimmunisierten Patienten durch Eculizumab
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Acute antibody-mediated rejection in sensitized renal transplant recipients

Decreased incidence in with eculizumab

Literatur

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    Gloor JM, Winters JL, Cornell LD et al (2010) Baseline donor-specific antibody levels and outcomes in positive crossmatch kidney transplantation. Am J Transplant 10:582–589PubMedCrossRefGoogle Scholar
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    Lefaucher C, Loupy A, Hill GS et al (2010) Preexisting donor-specific HLA antibodies predict outcome in kidney transplantation. J Am Soc Nephrol 21:1398–1406CrossRefGoogle Scholar
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    Stegall MD, Gloor J, Winters JL et al (2006) A comparison of plasmapheresis vs high-dose IVIG desensitization in renal allograft recipients with high levels of donor specific alloantibody. Am J Transplant 6:346–351PubMedCrossRefGoogle Scholar
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    Vo AA, Lukovsky M, Toyoda M et al (2008) Rituximab and intravenous immune globulin for desensitization during renal transplantation. N Engl J Med 359:242–251PubMedCrossRefGoogle Scholar
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    Wang H, Arp J, Liu W et al (2007) Inhibition of terminal complement components in presensitized transplant models prevents antibody mediated rejection leading to long-term graft survival and accommodation. J Immunol 179:4451–4463PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Zentrum für Kinder- und JugendmedizinUniversitätsklinikum HeidelbergHeidelbergDeutschland

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