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La radiologia medica

, Volume 122, Issue 9, pp 651–655 | Cite as

Role of core needle biopsy in primary breast lymphoma

  • Giulia Bicchierai
  • Luigi Rigacci
  • Vittorio Miele
  • Icro Meattini
  • Diego De Benedetto
  • Valeria Selvi
  • Simonetta Bianchi
  • Lorenzo Livi
  • Jacopo Nori
BREAST RADIOLOGY

Abstract

Primary breast lymphoma (PBL) may mimic carcinoma clinically and also mammographic and ecographic distinction is subtle. Despite its rarity, incidence of PBLs has increased over the last four decades and continues to increase for younger women and for some subtypes, and for this reason it is increasingly important to achieve a preoperative pathological diagnosis using core needle biopsy (CNB) or fine-needle aspiration cytology (FNA). The aim of this retrospective study was to report our single-center experience in CNBs performed for histological diagnosis of PBL compared to FNA. From a total of 10,500 CNBs we found seven patients affected by PBL diagnosed at Careggi Florence University Hospital, between January 2000 and December 2016. Diffuse large B cell lymphoma (DLBCL) was the most frequent PBLs and on CNBs specimens was possible do the fluorescent in situ hybridization analysis to evaluate the presence of chromosomal translocation. CNB is an effective method for the assessment of PBLs, especially for DLBCL, in which a correct and fast classification could change the therapeutic approach and the prognosis.

Keywords

Breast cancer Core needle biopsy Primary lymphoma Diagnosis 

Notes

Compliance with ethical standards

Conflict of interest

All the authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

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Copyright information

© Italian Society of Medical Radiology 2017

Authors and Affiliations

  • Giulia Bicchierai
    • 1
  • Luigi Rigacci
    • 2
  • Vittorio Miele
    • 3
  • Icro Meattini
    • 4
  • Diego De Benedetto
    • 1
  • Valeria Selvi
    • 1
  • Simonetta Bianchi
    • 5
  • Lorenzo Livi
    • 4
  • Jacopo Nori
    • 1
  1. 1.Diagnostic Senology UnitAzienda Ospedaliero-Universitaria CareggiFlorenceItaly
  2. 2.Hematology DepartmentAzienda Ospedaliero-Universitaria Careggi Florence, University of FlorenceFlorenceItaly
  3. 3.Emergency Radiology, DepartmentAzienda Ospedaliero-Universitaria Careggi FlorenceFlorenceItaly
  4. 4.Radiation Oncology Unit, Oncology DepartmentAzienda Ospedaliero-Universitaria Careggi Florence, University of FlorenceFlorenceItaly
  5. 5.Division of Pathological AnatomyUniversity of FlorenceFlorenceItaly

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