Strategies for Improving Influenza Immunization Rates among Hard-to-Reach Populations
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Abstract
Whereas considerable attention has been devoted to achieving high levels of influenza immunization, the importance of this issue is magnified by concern over pandemic influenza. Most recommendations for vaccine administration address high risk groups such as the elderly and those with chronic diseases, but coverage for hard-to-reach (HTR) populations has had less attention. HTR populations include minorities but also include other primarily urban groups such as undocumented immigrants, substance users, the homeless, and homebound elderly. Obstacles to the provision of immunization to HTR populations are present at the patient, provider, and structural levels. Strategies at the individual level for increasing immunization coverage include community-based educational campaigns to improve attitudes and increase motivation for receiving vaccine; at the provider level, education of providers to encourage immunizations, improving patient–provider interactions, broadening the provider base to include additional nurses and pharmacists, and adoption of standing orders for immunization administration; and at the structural level, promoting wider availability of and access to vaccine. The planning process for an influenza pandemic should include community engagement and extension of strategies beyond traditional providers to involve community-based organizations addressing HTR populations.
Keywords
Immunization Influenza Vaccination High-risk populations Hard-to-reach populations PandemicNotes
Acknowledgments
The authors’ contributions are as follows: David Vlahov conceived the project and led with the writing of the manuscript, Micaela H. Coady was the project director for the review and contributed to the writing, and Danielle C. Ompad and Sandro Galea contributed to the writing of the manuscript. We are grateful to Jeremiah A. Barondess, MD for reviewing this manuscript.
Researchers at the Center for Urban Epidemiologic Studies at The New York Academy of Medicine hosted a day-long meeting on optimizing strategies to vaccinate HTR populations in September 2006. Meeting participants made presentations and participated in discussion, but the sole responsibility for the content of this manuscript is that of the authors and does not represent the view of individual participants nor the official position of any of the institutions represented at the meeting. Participants were (in alphabetical order): Deborah Alfano (Merck); Nancy M. Bennett, MD, MS (University of Rochester Medical Center); Gus Birkhead, MD, MPH (New York State Department of Health); Elizabeth Blowers-Nyman (Merck); Nicholas Daniels, MD, MPH (University of California San Francisco); Kristine Gebbie, DrPH, RN (Columbia University); Bruce Gellin, MD, MPH (Health and Human Services); John Grabenstein, RPh, PhD (Merck); Neal Halsey, MD (Johns Hopkins); Patrick Kelley, MD, DrPH (Institute of Medicine); Sarah Landry, MA (GlaxoSmithKline); Arnold Monto, MD (University of Michigan); Stephanie G. Phillips, PhD (Project House); Anne Schuchat, MD (Centers for Disease Control and Prevention); Shelagh Weatherill, BScN, MA (Vancouver Coastal Health); Isaac Weisfuse, MD, MPH (New York City Department of Health and Mental Hygiene); Richard K. Zimmerman, MD, MPH (University of Pittsburgh), and Jane R. Zucker, MD, MSc (New York City Department of Health and Mental Hygiene).
This meeting was convened as part of Project VIVA (Venue-Intensive Vaccines for Adults), a multilevel community participatory intervention developed by members of the Harlem Community and Academic Partnership (HCAP) and the Center for Urban Epidemiologic Studies (CUES). The VIVA Intervention Working Group members are: Ann Boyer (Mt. Sinai Medical Center, Women’s Information Network and Birdsong); Robert Brackbill (New York City Department of Health and Mental Hygiene); Brian Brown (Harm Reduction Educators); Jose Caraballo (Palladia, Inc.); Micaela Coady (CUES); Sandro Galea (CUES); Katherine Glidden (CUES); Karyn London (Mt. Sinai Medical Center); Gail Love (Women’s Information Network); Pat Monahan (East Harlem Community Health Committee, Inc. and Little Sisters of the Assumption Family Health Services); Danielle Ompad (CUES); Erica Phillips (Weill Cornell Medical College, New York Presbyterian Hospital); Sarah Sisco (CUES); Sharon Stancliff (Harm Reduction Coalition); David Vlahov (CUES), and Linda Weiss (Office of Special Populations at the New York Academy of Medicine). This work was supported by a grant from the National Institute on Drug Abuse (DA017004) and the Merck Foundation.
References
- 1.Thompson WW, Shay DK, Weintraub E et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA. 2003;289(2):179–186.CrossRefPubMedGoogle Scholar
- 2.Fedson DS. Influenza prevention and control. Past practices and future prospects. Am J Med. 1987;82(6A):42–47.CrossRefPubMedGoogle Scholar
- 3.Smith NM, Bresee JS, Shay DK, Uyeki TM, Cox NJ, Strikas RA. Prevention and control of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Morb Mortal Wkly Rep. 2006;55(RR-10):1–42.Google Scholar
- 4.Simonsen L, Clarke MJ, Schonberger LB, Arden NH, Cox NJ, Fukuda K. Pandemic versus epidemic influenza mortality: a pattern of changing age distribution. J Infect Dis. 1998;178(1):53–60.PubMedGoogle Scholar
- 5.Centers for Disease Control and Prevention. National Health Interview Survey 2006; Accessed on December 1, 2006. Available at: http://www.cdc.gov/nchs/nhis.htm.
- 6.Ostbye T, Taylor DH, Lee AM, Greenberg G, van SL. Racial differences in influenza vaccination among older Americans 1996–2000: longitudinal analysis of the Health and Retirement Study (HRS) and the Asset and Health Dynamics Among the Oldest Old (AHEAD) survey. BMC Public Health. 2003;3(41):41.CrossRefPubMedGoogle Scholar
- 7.Bryant WK, Ompad DC, Sisco S et al. Determinants of influenza vaccination in hard-to-reach urban populations. Prev Med. 2006;43(1):60–70.CrossRefPubMedGoogle Scholar
- 8.Centers for Disease Control and Prevention. Influenza and pneumococcal vaccination coverage among persons aged > or =65 years and persons aged 18–64 years with diabetes or asthma—United States, 2003. MMWR Morb Mortal Wkly Rep. 2004;53(43):1007–1012.Google Scholar
- 9.Zimmerman RK, Middleton DB. Vaccines for persons at high risk due to medical conditions, occupation, environment, or lifestyle, 2005. J Fam Pract. 2005;54(1 Suppl):S27–S36.PubMedGoogle Scholar
- 10.Regidor E, Calle ME, Navarro P, Dominguez V. The size of educational differences in mortality from specific causes of death in men and women. Eur J Epidemiol. 2003;18(5):395–400.CrossRefPubMedGoogle Scholar
- 11.World Health Organization. Global pandemic influenza action plan to increase vaccine supply. Accessed on: December 1, 2006. Available at: http://www.who.int/vaccines-documents/DocsPDF06/863.pdf; 2006.
- 12.Kieny MP, Costa A, Hombach J et al. A global pandemic influenza vaccine action plan. Vaccine. 2006;24(40–41):6367–6370 September 29.CrossRefPubMedGoogle Scholar
- 13.Nichol KL, Treanor JJ. Vaccines for seasonal and pandemic influenza. J Infect Dis. 2006;194(Suppl 2):S111–S118.CrossRefPubMedGoogle Scholar
- 14.Booy R, Brown LE, Grohmann GS, Macintyre CR. Pandemic vaccines: promises and pitfalls. Med J Aust. 2006;185(10):S62–S65.PubMedGoogle Scholar
- 15.Centers for Disease Control and Prevention. Vaccine-preventable diseases: improving coverage in children, adolescents and adults. MMWR Morb Mortal Wkly Rep. 1999;48(RR-8):1–15.Google Scholar
- 16.Ompad DC, Galea S, Vlahov D. Distribution of influenza vaccine to high-risk groups. Epidemiol Rev. 2006;28:54–70. Epub 2006 May 17.:54–70.CrossRefPubMedGoogle Scholar
- 17.Briss PA, Rodewald LE, Hinman AR et al. Reviews of evidence regarding interventions to improve vaccination coverage in children, adolescents, and adults. The Task Force on Community Preventive Services. Am J Prev Med. 2000;18(1 Suppl):97–140.CrossRefPubMedGoogle Scholar
- 18.Passel JS. The size and the characteristics of the unauthorized migrant population in the U.S. Pew Hispanic Center; March 2006.Google Scholar
- 19.Holmberg SD. The estimated prevalence and incidence of HIV in 96 large US metropolitan areas. Am J Public Health. 1996;86(5):642–654.PubMedCrossRefGoogle Scholar
- 20.Homeless Research Institute. Homelessness Counts. Accessed January 31, 2007. Available at: http://www.endhomelessness.org/content/general/detail/1440; 2007.
- 21.Figaro MK, Belue R. Prevalence of influenza vaccination in a high-risk population: impact of age and race. J Ambul Care Manage. 2005;28(1):24–29 January.PubMedGoogle Scholar
- 22.Collins KS, Hughes D, Doty M, Ives B, Edwards J, Tenney K. Diverse Communities, Common Concerns: Assessing Health Care Quality for Minority Americans. The Commonwealth Fund; March 2002.Google Scholar
- 23.Zimmerman RK, Santibanez TA, Janosky JE et al. What affects influenza vaccination rates among older patients? An analysis from inner-city, suburban, rural, and Veterans Affairs practices. Am J Med. 2003;114(1):31–38.CrossRefPubMedGoogle Scholar
- 24.Nowalk MP, Zimmerman RK, Tabbarah M, Raymund M, Jewell IK. Determinants of adult vaccination at inner-city health centers: a descriptive study. BMC Fam Pract. 2006;7(2):2 January 10.CrossRefPubMedGoogle Scholar
- 25.Burnett M, Genao I, Wong WF. Race, culture, and trust: why should I take a shot if I’m not sick? Ethn Dis. 2005;15(2 Suppl 3):S3.PubMedGoogle Scholar
- 26.Armstrong K, Berlin M, Schwartz JS, Propert K, Ubel PA. Barriers to influenza immunization in a low-income urban population. Am J Prev Med. 2001;20(1):21–25.CrossRefPubMedGoogle Scholar
- 27.Berk ML, Schur CL. The effect of fear on access to care among undocumented Latino immigrants. J Immigr Health. 2001;3(3):151–156.CrossRefPubMedGoogle Scholar
- 28.Zimmerman RK, Nowalk MP, Raymund M et al. Tailored interventions to increase influenza vaccination in neighborhood health centers serving the disadvantaged. Am J Public Health. 2003;93(10):1699–1705.PubMedGoogle Scholar
- 29.Daniels NA, Juarbe T, Rangel-Lugo M, Moreno-John G, Perez-Stable EJ. Focus group interviews on racial and ethnic attitudes regarding adult vaccinations. J Natl Med Assoc. 2004;96(11):1455–1461.PubMedGoogle Scholar
- 30.Grabenstein JD, Guess HA, Hartzema AG, Koch GG, Konrad TR. Attitudinal factors among adult prescription recipients associated with choice of where to be vaccinated. J Clin Epidemiol. 2002;55(3):279–284.CrossRefPubMedGoogle Scholar
- 31.LaVela SL, Smith B, Weaver FM, Legro MW, Goldstein B, Nichol K. Attitudes and practices regarding influenza vaccination among healthcare workers providing services to individuals with spinal cord injuries and disorders. Infect Control Hosp Epidemiol. 2004;25(11):933–940.CrossRefPubMedGoogle Scholar
- 32.Silverman M, Terry MA, Zimmerman RK, Nutini JF, Ricci EM. Tailoring interventions: understanding medical practice culture. J Cross-Cult Gerontol. 2004;19(2):47–76.CrossRefPubMedGoogle Scholar
- 33.Lindley MC, Wortley PM, Winston CA, Bardenheier BH. The role of attitudes in understanding disparities in adult influenza vaccination. Am J Prev Med. 2006;31(4):281–285.CrossRefPubMedGoogle Scholar
- 34.Nichol KL, Lofgren RP, Gapinski J. Influenza vaccination. Knowledge, attitudes, and behavior among high-risk outpatients. Arch Intern Med. 1992;152(1):106–110.CrossRefPubMedGoogle Scholar
- 35.Hebert PL, Frick KD, Kane RL, McBean AM. The causes of racial and ethnic differences in influenza vaccination rates among elderly Medicare beneficiaries. Health Serv Res. 2005;40(2):517–537.CrossRefPubMedGoogle Scholar
- 36.Winston CA, Wortley PM, Lees KA. Factors associated with vaccination of medicare beneficiaries in five U.S. communities: results from the racial and ethnic adult disparities in immunization initiative survey, 2003. J Am Geriatr Soc. 2006;54(2):303–310.CrossRefPubMedGoogle Scholar
- 37.Takayanagi IJ, Cardoso MR, Costa SF, Araya ME, Machado CM. Attitudes of health care workers to influenza vaccination: why are they not vaccinated? Am J Infect Control. 2007;35(1):56–61.CrossRefPubMedGoogle Scholar
- 38.Nichol KL. Ten-year durability and success of an organized program to increase influenza and pneumococcal vaccination rates among high-risk adults. Am J Med. 1998;105(5):385–392.CrossRefPubMedGoogle Scholar
- 39.Nichol KL, Korn JE, Margolis KL, Poland GA, Petzel RA, Lofgren RP. Achieving the national health objective for influenza immunization: success of an institution-wide vaccination program. Am J Med. 1990;89(2):156–160.CrossRefPubMedGoogle Scholar
- 40.Stancliff S, Salomon N, Perlman DC, Russell PC. Provision of influenza and pneumococcal vaccines to injection drug users at a syringe exchange. J Subst Abuse Treat. 2000;18(3):263–265.CrossRefPubMedGoogle Scholar
- 41.Weatherill SA, Buxton JA, Daly PC. Immunization programs in non-traditional settings. Can J Public Health. 2004;95(2):133–137.PubMedGoogle Scholar
- 42.Findley SE, Irigoyen M, Sanchez M et al. Community-based strategies to reduce childhood immunization disparities. Health Promot Pract. 2006;7(3 Suppl):191S–200S.CrossRefPubMedGoogle Scholar
- 43.Jernigan DH, Wright PA. Media advocacy: lessons from community experiences. J Public Health Policy. 1996;17(3):306–330.CrossRefPubMedGoogle Scholar
- 44.Hanna JN, Young DM, Brookes DL, Dostie BG, Murphy DM. The initial coverage and impact of the pneumococcal and influenza vaccination program for at-risk indigenous adults in Far North Queensland. Aust N Z J Public Health. 2001;25(6):543–546.PubMedGoogle Scholar
- 45.Barker WH, Bennett NM, LaForce FM, Waltz EC, Weiner LB. "McFlu". The Monroe County, New York, Medicare vaccine demonstration. Am J Prev Med. 1999;16(3 Suppl):118–127.CrossRefPubMedGoogle Scholar
- 46.Kicera TJ, Douglas M, Guerra FA. Best-practice models that work: the CDC’s Racial and Ethnic Adult Disparities Immunization Initiative (READII) Programs. Ethn Dis. 2005;15(2 Suppl 3):S3.PubMedGoogle Scholar
- 47.Gaglani M, Riggs M, Kamenicky C, Glezen WP. A computerized reminder strategy is effective for annual influenza immunization of children with asthma or reactive airway disease. Pediatr Infect Dis J. 2001;20(12):1155–1160.CrossRefPubMedGoogle Scholar
- 48.Kouides RW, Bennett NM, Lewis B, Cappuccio JD, Barker WH, LaForce FM. Performance-based physician reimbursement and influenza immunization rates in the elderly. The Primary-Care Physicians of Monroe County. Am J Prev Med. 1998;14(2):89–95.CrossRefPubMedGoogle Scholar
- 49.Lawson F, Baker V, Au D, McElhaney JE. Standing orders for influenza vaccination increased vaccination rates in inpatient settings compared with community rates. J Gerontol A Biol Sci Med Sci. 2000;55(9):M522–M526.PubMedGoogle Scholar
- 50.Dexter PR, Perkins SM, Maharry KS, Jones K, McDonald CJ. Inpatient computer-based standing orders vs physician reminders to increase influenza and pneumococcal vaccination rates: a randomized trial. JAMA. 2004;292(19):2366–2371.CrossRefPubMedGoogle Scholar
- 51.Steyer TE, Ragucci KR, Pearson WS, Mainous AG III. The role of pharmacists in the delivery of influenza vaccinations. Vaccine. 2004;22(8):1001–1006.CrossRefPubMedGoogle Scholar
- 52.Gust ID, Hampson AW, Lavanchy D. Planning for the next pandemic of influenza. Rev Med Virol. 2001;11(1):59–70.CrossRefPubMedGoogle Scholar
- 53.Ghendon Y. Influenza vaccines: a main problem in control of pandemics. Eur J Epidemiol. 1994;10(4):485–486.CrossRefPubMedGoogle Scholar
- 54.Ulmer JB, Valley U, Rappuoli R. Vaccine manufacturing: challenges and solutions. Nat Biotechnol. 2006;24(11):1377–1383.CrossRefPubMedGoogle Scholar
- 55.Tan L. Strengthening the supply of routinely recommended vaccines in the United States: a perspective from the American Medical Association. Clin Infect Dis. 2006;42(Suppl 3):S121–S124.CrossRefPubMedGoogle Scholar
- 56.Appel A, Everhart R, Mehler PS, MacKenzie TD. Lack of ethnic disparities in adult immunization rates among underserved older patients in an urban public health system. Med Care. 2006;44(11):1054–1058.CrossRefPubMedGoogle Scholar
- 57.Rimple D, Weiss SJ, Brett M, Ernst AA. An emergency department-based vaccination program: overcoming the barriers for adults at high risk for vaccine-preventable diseases. Acad Emerg Med. 2006;13(9):922–930.CrossRefPubMedGoogle Scholar
- 58.Coady MH, Weiss L, Galea S, Ompad DC, Glidden K, Vlahov D. Rapid vaccine distribution in non-traditional settings: lessons learned from Project VIVA. J Community Health Nurs. 2007 (In press).Google Scholar
- 59.Longini IM Jr., Halloran ME. Strategy for distribution of influenza vaccine to high-risk groups and children. Am J Epidemiol. 2005;161(4):303–306.CrossRefPubMedGoogle Scholar
- 60.Hurwitz ES, Haber M, Chang A et al. Effectiveness of influenza vaccination of day care children in reducing influenza-related morbidity among household contacts. JAMA. 2000;284(13):1677–1682.CrossRefPubMedGoogle Scholar
- 61.Glezen WP. Herd protection against influenza. J Clin Virol. 2006;37(4):237–243.CrossRefPubMedGoogle Scholar
- 62.Weycker D, Edelsberg J, Halloran ME et al. Population-wide benefits of routine vaccination of children against influenza. Vaccine. 2005;23(10):1284–1293.CrossRefPubMedGoogle Scholar
- 63.US Department of Health and Human Services. HHS pandemic influenza plan. Accessed on December 1, 2006. Available at: http://www.hhs.gov/pandemicflu/plan; 2005.
- 64.U.S.Homeland Security Council. National Strategy for Pandemic Influenza. Accessed on November 15, 2006. Available at: http://www.whitehouse.gov/homeland/nspi.pdf; 2005.
- 65.Schwartz B, Wortley P. Mass vaccination for annual and pandemic influenza. Curr Top Microbiol Immunol. 2006;304:131–152.PubMedCrossRefGoogle Scholar
- 66.Chin TW, Chant C, Tanzini R, Wells J. Severe acute respiratory syndrome (SARS): the pharmacist’s role. Pharmacotherapy. 2004;24(6):705–712.CrossRefPubMedGoogle Scholar
- 67.Weisfuse IB, Berg D, Gasner R, Layton M, Misener M, Zucker JR. Pandemic influenza planning in New York City. J Urban Health. 2006;83(3):351–354.CrossRefPubMedGoogle Scholar
- 68.Whitley RJ, Bartlett J, Hayden FG, Pavia AT, Tapper M, Monto AS. Seasonal and pandemic influenza: recommendations for preparedness in the United States. J Infect Dis. 2006;194(Suppl 2):S155–S161.CrossRefPubMedGoogle Scholar
- 69.Cinti S. Pandemic influenza: are we ready? Disaster Manag Response. 2005;3(3):61–67.CrossRefPubMedGoogle Scholar
- 70.Webby RJ, Webster RG. Are we ready for pandemic influenza? Science. 2003;302(5650):1519–1522.CrossRefPubMedGoogle Scholar
- 71.Health Systems Research, Inc. Providing mass medical care with scarce resources: a community planning guide. Accessed on January 31, 2007. Available at: http://www.ahrq.gov/research/mce/mceguide.pdf; 2006.
- 72.New York City Department of Health and Mental Hygiene. NYCDOHMH Pandemic Influenza Preparedness and Response Plan. Accessed on January 31, 2007.Available at: http://www.nyc.gov/html/doh/downloads/pdf/cd/cd-panflu-plan.pdf; 2006.
- 73.Dransfield MT, Bailey WC. COPD: racial disparities in susceptibility, treatment, and outcomes. Clin Chest Med. 2006;27(3):463–471.CrossRefPubMedGoogle Scholar
- 74.Asch S, Leake B, Gelberg L. Does fear of immigration authorities deter tuberculosis patients from seeking care? West J Med. 1994;161(4):373–376.PubMedGoogle Scholar
- 75.Sambamoorthi U, Findley PA. Who are the elderly who never receive influenza immunization? Prev Med. 2005;40(4):469–478.CrossRefPubMedGoogle Scholar
- 76.Whitfield KE. Studying biobehavioral aspects of health disparities among older adult minorities. J Urban Health. 2005;82(2 Suppl 3):iii103–iii110.Google Scholar
- 77.Russell ML, Maxwell CJ. The prevalence and correlates of influenza vaccination among a home care population. Can J Public Health. 2000;91(6):441–444.PubMedGoogle Scholar
- 78.Singleton JA, Poel AJ, Lu PJ, Nichol KL, Iwane MK. Where adults reported receiving influenza vaccination in the United States. Am J Infect Control. 2005;33(10):563–570.CrossRefPubMedGoogle Scholar
- 79.D’Heilly SJ, Blade MA, Nichol KL. Safety of influenza vaccinations administered in nontraditional settings. Vaccine. 2006;24(18):4024–4027.CrossRefPubMedGoogle Scholar
- 80.Larson E. Racial and ethnic disparities in immunizations: recommendations for clinicians. Fam Med. 2003;35(9):655–660.PubMedGoogle Scholar
- 81.Grabenstein JD, Guess HA, Hartzema AG, Koch GG, Konrad TR. Effect of vaccination by community pharmacists among adult prescription recipients. Med Care. 2001;39(4):340–348.CrossRefPubMedGoogle Scholar