Medical & Biological Engineering & Computing

, Volume 49, Issue 11, pp 1347–1352

Direct metal laser sintering (DMLS) of a customized titanium mesh for prosthetically guided bone regeneration of atrophic maxillary arches

  • L. Ciocca
  • M. Fantini
  • F. De Crescenzio
  • G. Corinaldesi
  • R. Scotti
Technical Note


This study describes a protocol for the direct manufacturing of a customized titanium mesh using CAD–CAM procedures and rapid prototyping to augment maxillary bone and minimize surgery when severe atrophy or post-oncological deformities are present. Titanium mesh and particulate autogenous plus bovine demineralised bone were planned for patient rehabilitation. Bone augmentation planning was performed using the pre-op CT data set in relation to the prosthetic demands, minimizing the bone volume to augment at the minimum necessary for implants. The containment mesh design was used to prototype the 0.6 mm thickness customized titanium mesh, by direct metal laser sintering. The levels of regenerated bone were calculated using the post-op CT data set, through comparison with the pre-op CT data set. The mean vertical height difference of the crestal bone was 2.57 mm, while the mean buccal-palatal dimension of thickness difference was 3.41 mm. All planned implants were positioned after an 8 month healing period using two-step implant surgery, and finally restored with a partial fixed prosthesis. We present a viable and reproducible method to determine the correct bone augmentation prior to implant placement and CAD–CAM to produce a customized direct laser-sintered titanium mesh that can be used for bone regeneration.


Bone augmentation Titanium mesh Implant surgery CAD–CAM Rapid prototyping 


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Copyright information

© International Federation for Medical and Biological Engineering 2011

Authors and Affiliations

  • L. Ciocca
    • 1
  • M. Fantini
    • 2
  • F. De Crescenzio
    • 2
  • G. Corinaldesi
    • 3
  • R. Scotti
    • 4
  1. 1.Section of Prosthodontics, Department of Oral ScienceAlma Mater Studiorum, University of BolognaBolognaItaly
  2. 2.Virtual Reality and Simulation Laboratory, Second Engineering FacultyAlma Mater Studiorum, University of BolognaForlìItaly
  3. 3.Section of Oral and Maxillofacial Surgery, Department of Oral ScienceAlma Mater Studiorum, University of BolognaBolognaItaly
  4. 4.Oral and Maxillo-Facial Rehabilitation, Section of Prosthodontics, Department of Oral ScienceAlma Mater Studiorum, University of BolognaBolognaItaly

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