Patient-specific computational fluid dynamics: structured mesh generation from coronary angiography
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Patient-specific simulations are widely used to investigate the local hemodynamics within realistic morphologies. However, pre-processing and mesh generation are time consuming, operator dependent, and the quality of the resulting mesh is often suboptimal. Therefore, a semi-automatic methodology for patient-specific reconstruction and structured meshing of a left coronary tree from biplane angiography is presented. Seven hexahedral grids have been generated with the new method (50,000–3,200,000 cells) and compared to nine unstructured tetrahedral grids with prismatic boundary layer (150,000–3,100,000 cells). Steady-state blood flow simulation using Computational Fluid Dynamics (CFD) has been used to calculate the Wall Shear Stress (WSS). Our results (99 percentile, area-weighted and local WSS values along a line) demonstrate that hexahedral meshes with respect to tetrahedral/prismatic meshes converge better, and for the same accuracy of the result, six times less cells and 14 times less computational time are required. Hexahedral meshes are superior to tetrahedral/prismatic meshes and should be preferred for the calculation of the WSS.
KeywordsPatient-specific Structured hexahedral mesh Biplane angiography pyFormex CFD
The authors thank Dr. Yves Taeymans, PhD, Bram Trachet, and Thomas De Schryver for their valuable support, and the Philips Medical System Nederland B.V., Best, The Netherlands.
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