Towards assessing the sympathovagal balance

  • Melvyn J. Lafitte
  • Orin R. Sauvageot
  • Marion Fevre-Genoulaz
  • Marc Zimmermann
Original Article

Abstract

Exact assessment of the autonomic nervous system’s (ANS) activity by means of heart rate variability (HRV) is a long-standing challenge. Although many techniques have been proposed to take up the challenge, none ever proposed a rationale for the approach behind the technique or a satisfying discrimination of the two activities which underlie the autonomic control of HRV. We here propose a new method, providing both an understanding of the discrimination’s nature and a framework which we believe leads to a thorough assessment of the sympathovagal balance, as a trajectory between points in a well-chosen space. The methodology assumes tools from scale invariance/covariance physics. The sympathovagal balance is obtained on a beat-to-beat basis with the dynamics portrayed through a trajectory. Furthermore, universal trajectories are sought which would comprehensively describe the effect of atropine and isoproterenol injections on systems underlying the heart pace variations. Non-invasive assessment of the respective activities of the sympathetic and parasympathetic subsystems of the ANS would be possible through cardiac autonomic measurements.

Keywords

Non-invasive monitoring Autonomic nervous system Heart rate variability Theoretical physics Experimental mathematics 

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Copyright information

© International Federation for Medical and Biological Engineering 2006

Authors and Affiliations

  • Melvyn J. Lafitte
    • 1
    • 2
  • Orin R. Sauvageot
    • 1
  • Marion Fevre-Genoulaz
    • 1
  • Marc Zimmermann
    • 1
  1. 1.Cardiovascular DepartmentHôpital de la Tour MeyrinGenevaSwitzerland
  2. 2.DyansysAnièresSwitzerland

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