Development of a Health Related Quality of Life Measure for Adolescents and Young Adults Following Invasive Meningococcal Disease
This study describes the key areas that matter to adolescent survivors of Invasive Meningococcal Disease (IMD). Satisfaction with Life After Meningitis is a brief multidimensional measure of health related quality of life that is reliable and correlates with criterion variables in a theoretically meaningful way. To develop a Health Related Quality of Life (HRQoL) measure for adolescent and young adult survivors of (IMD) we used a cross-sectional study and focus groups. The study was conducted in two phases. In Phase 1 a pool of potential items were generated based on the following: a review of existing measures, focus groups with IMD survivors, and an expert group consultation. Phase 2 involved administration of the questionnaire to a sample of adolescent and young adult IMD survivors. Factor analysis suggested a correlated four factor solution: Wellbeing, Positive about Future, Social Support, and Confidence. These factors were significantly correlated in a theoretically predictable way with scores from the Beck Depression Inventory (correlations ranged from −0.77 to −0.81) and the eight domains of the SF-36 Health Survey (correlations ranged from 0.32 to 0.79). The reliability of all subscales was high ranging from 0.85 to 0.92. The Satisfaction with Life After Meningitis (SLAM) questionnaire is a HRQoL self-report measure that produces reliable scores and is appropriate for use with young survivors of IMD. There is also evidence of concurrent validity with existing measures of physical and psychological well-being.
KeywordsAdolescence Young adults Invasive meningococcal disease Health related quality of life Questionnaire
Beck depression inventory
Invasive meningococcal disease
Health related quality of life
Quality of life
Satisfaction with life after meningitis
The development of SLAM was funded by the Meningitis Trust. The Meningitis Trust were not involved in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the final manuscript.
We would like to thank all the young people who gave their time to meet with us and share their ideas and experiences.
The authors have no financial relationships relevant to this article to disclose.
Conflict of Interest
The authors have no conflicts of interest to disclose.
The study was funded by the Meningitis Trust
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