Applied Research in Quality of Life

, Volume 6, Issue 3, pp 311–324

Health Related Quality of Life After Percutaneous Coronary Revascularisation in Patients with Previous Coronary Artery Bypass Grafts: A Two-Year Follow Up Study

  • Girish N. Viswanathan
  • Gnanamoorthy Mayurathan
  • Tony Hildreth
  • Stephen G. Worthley
  • Azfar G. Zaman


Percutaneous coronary revascularisation [PCR] improves angina and health related quality of life [HRQOL] compared to standard medical therapy. It is unknown whether PCR has the same benefits for patients with a history of CABG. Over a period of 5 years, we assessed HRQOL of patients undergoing PCR using Part 1 of the Nottingham Health Profile [NHP] at baseline 3, 12 and 24 months. We compared HRQOL after PCR in 255 patients with CABG to 2680 without. There were more males [81.1% v 69.6% p = 0.002] and older patients [mean age 60.1 years v. 58.0 p = 0.03] in CABG group. Perceived HRQOL improved at 24 months for pain, energy and emotional reaction but the improvement was less in the CABG group. However, mean NHP scores at 24 months for those with CABG had returned to baseline levels for sleep [34.9] and for physical function was worse than at baseline [22.0 vs 30.7]. This relationship persisted after adjustment for male sex, history of previous MI and coronary stent usage. Patients with previous CABG had less improvement in HRQOL after PCR. Further work is needed to assess the benefits and cost effectiveness of PCR in these patients.


Percutaneous coronary revascularisation Coronary artery bypass surgery Health related quality of life Nottingham health profile 



World Health Organisation


Health related quality of life


Nottingham health profile questionnaire


Coronary artery disease


Percutaneous revascularisation


Coronary artery bypass surgery


Short form- 36 questionnaire


Seattle angina questionnaire

Copyright information

© Springer Science+Business Media B.V./The International Society for Quality-of-Life Studies (ISQOLS) 2010

Authors and Affiliations

  • Girish N. Viswanathan
    • 1
  • Gnanamoorthy Mayurathan
    • 2
  • Tony Hildreth
    • 3
    • 5
  • Stephen G. Worthley
    • 4
  • Azfar G. Zaman
    • 1
    • 2
  1. 1.Institute of Cellular MedicineNewcastle UniversityNewcastle upon TyneUK
  2. 2.Freeman HospitalNewcastle upon TyneUK
  3. 3.Research and Development, City HospitalSunderlandUK
  4. 4.Adelaide University and Royal Adelaide HospitalAdelaideSouth Australia
  5. 5.Northumbria UniversityNewcastle upon TyneUK

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