Observations on potential novel transcripts from RNA-Seq data

Research Article


With the rapid development of next generation deep sequencing technologies, sequencing cDNA reverse-transcribed from RNA molecules (RNA-Seq) has become a key approach in studying gene expression and transcriptomes. Because RNA-Seq does not rely on annotation of known genes, it provides the opportunity of discovering transcripts that have not been annotated in current databases. Studying the distribution of RNASeq signals and a systematic view on the potential new transcripts revealed from the signals is an important step toward the understanding of transcriptomes.


RNA-Seq novel transcripts next generation sequencing bioinformatics 


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Copyright information

© Higher Education Press and Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  1. 1.Key Laboratory of Bioinformatics and Bioinformatics Division, Ministry of Education, Tsinghua National Laboratory for Information Science and Technology/Department of AutomationTsinghua UniversityBeijingChina

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