Abstract
In this research, a nanoscale DNA structure of analogic China map is created. The nanostructure of roughly 150 nm in diameter with a spatial resolution of 6 nm is purely constructed by folding DNA. The picture observed by atomic force microscopy (AFM) is almost identical with the designed shape. The DNA origami technology invented by Rothemund in 2006 is employed in the construction of this shape, which has proved the capability of constructing almost any complicated shape enabled by DNA origami, and provides new bottom-up method for constructing nanostructures.
Keywords
DNA origami self-assembly nanostructure China map AFMPreview
Unable to display preview. Download preview PDF.
References
- 1.Seeman N C. Nanoscale assembly and manipulation of branched DNA: A biological starting point for nanotechnology. In: Lewis J, Quel J L, et al, eds. Nanocon Proceedings. Bellevue: NANOCON, 1989. 101–107.Google Scholar
- 2.Yan H, Reif J H, LaBean T H. DNA-templated self-assembly of protein arrays and highly conductive nanowires. Science, 2003, 301: 1882–1884CrossRefGoogle Scholar
- 3.Winfree E, Liu F, Seeman N C, et al. Design and self-assembly of two-dimensional DNA crystals. Nature, 1998, 394: 539–544CrossRefGoogle Scholar
- 4.Rothemund P W. Papadakis N, Winfree E. Algorithmic self-assembly of DNA Sierpinski triangles. PLoS Biol, 2004, 2: 2041–2053CrossRefGoogle Scholar
- 5.Rothemund P W, Ekani-Nkodo A, Winfree E, et al. Design and characterization of programmable DNA nanotubes. JACS, 2004, 126: 16344–16352CrossRefGoogle Scholar
- 6.LaBean T H, Reif J H, Seeman N C, et al. Construction, analysis, ligation, and self-assembly of DNA triple crossover complexes. JACS, 2000, 122: 1848–1860CrossRefGoogle Scholar
- 7.Rothemund P W. Folding DNA to create nanoscale shapes and patterns. Nature, 2006, 440: 297–302CrossRefGoogle Scholar
Copyright information
© Science in China Press 2006