Science China Chemistry

, Volume 55, Issue 1, pp 50–54

Iron-mediated cross dehydrogenative coupling (CDC) of terminal alkynes with benzylic ethers and alkanes

  • Shi-Kai Xiang
  • Bo Zhang
  • Li-He Zhang
  • YuXin Cui
  • Ning Jiao
Articles Special Topic The Frontiers of Chemical Biology and Synthesis

DOI: 10.1007/s11426-011-4435-3

Cite this article as:
Xiang, SK., Zhang, B., Zhang, LH. et al. Sci. China Chem. (2012) 55: 50. doi:10.1007/s11426-011-4435-3

Abstract

Iron-mediated sp-sp3 C-C bond formation through the cross dehydrogenative coupling (CDC) of terminal alkynes with benzylic ethers or alkanes has been developed. The inexpensive iron salt is used as the catalyst to make this transformation environmentally benign.

Keywords

iron cross dehydrogenative coupling terminal alkynes benzylic ethers 

Copyright information

© Science China Press and Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Shi-Kai Xiang
    • 1
  • Bo Zhang
    • 1
  • Li-He Zhang
    • 1
  • YuXin Cui
    • 1
  • Ning Jiao
    • 1
    • 2
  1. 1.State Key Laboratory of Natural and Biomimetic Drugs; School of Pharmaceutical SciencesPeking UniversityBeijingChina
  2. 2.Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of ChemistryEast China Normal UniversityShanghaiChina

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