HSS Journal

, Volume 8, Issue 1, pp 54–56 | Cite as

Novel Quantitative Imaging for Early Detection of Joint Tissue Injury to Support Early Treatment Strategies

  • Patricia C. Stepp
  • Ashley A. Williams
  • Constance Chu
HSS Osteoarthritis symposium: frontiers in OA


MRI OCT cartilage 


  1. 1.
    Bear DM, Williams A, Chu CT, Coyle CH, Chu CR: Optical Coherence Tomography Grading Correlates with MRI T2 Mapping and Extracellular Matrix Content. Journal of Orthopaedic Research 2010, 28(4):546–552.PubMedGoogle Scholar
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    Chu CR, Williams A, Tolliver D, Kwoh CK, Bruno S, 3rd, Irrgang JJ: Clinical optical coherence tomography of early articular cartilage degeneration in patients with degenerative meniscal tears. Arthritis Rheum 2010, 62(5):1412–1420.PubMedGoogle Scholar
  3. 3.
    Williams A, Qian Y, Bear D, Chu CR: Assessing degeneration of human articular cartilage with ultra-short echo time (UTE) T2* mapping. Osteoarthritis Cartilage 2010, 18(4):539–546.PubMedCrossRefGoogle Scholar
  4. 4.
    Chu CR, Williams AA, Y. Q: Novel MRI Ultrashort TE Enhanced T2* Mapping Shows Subsurface Cartilage and Meniscus Changes Clinically in Human Subjects After Anterior Cruciate Ligament Tear (ACLT). In: Proceedings of the American College of Rheumatology Annual Scientific Meeting: November 2011; Chicago, IL; 2011Google Scholar
  5. 5.
    Williams AA, Coyle CH, Bruno S, Fu F, West R, Chu CR: OCT predicts T2 change over 6 and 12 months in subjects with early articular cartilage degeneration. Proceedings of the Orthopaedic Research Society Annual Meeting 2011:96Google Scholar
  6. 6.
    Williams A, Qian Y, Chu CR: Clinical ultra-short TE-enhanced T2* mapping of meniscus. In: Proceedings of the 19th Annual Meeting of the International Society for Magnetic Resonance in Medicine: May 2011; Montreal, CA; 2011Google Scholar
  7. 7.
    Williams A, Qian Y, Chu CR: UTE-T2 * mapping of human articular cartilage in vivo: a repeatability assessment. Osteoarthritis Cartilage 2011, 19(1):84–88PubMedCrossRefGoogle Scholar

Copyright information

© Hospital for Special Surgery 2012

Authors and Affiliations

  • Patricia C. Stepp
    • 1
  • Ashley A. Williams
    • 1
  • Constance Chu
    • 1
  1. 1.Cartilage Restoration Center, Department of Orthopaedic SurgeryUniversity of PittsburghPittsburghUSA

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