A case of death caused by abuse of a synthetic cannabinoid N-1-naphthalenyl-1-pentyl-1H-indole-3-carboxamide
- 352 Downloads
A man aged in his twenties was found dead on the floor in his room. A package containing dried herbal blend labeled “Fairy evolution” and smoking devices were found in the room. The postmortem interval of the deceased was estimated to be 3 days. The autopsy disclosed no marked findings explaining the cause of death. Toxicological analyses by gas chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry revealed the presence of N-1-naphthalenyl-1-pentyl-1H-indole-3-carboxamide (NNEI) in the herbal blend and in specimens taken from the victim. The concentrations in the blood and adipose tissue specimens were 0.64–0.99 and 42.9 ng/ml, respectively. To our knowledge, this is the first report to describe NNEI concentrations in human specimens in the fatal poisoning case.
KeywordsN-1-Naphthalenyl-1-pentyl-1H-indole-3-carboxamide NNEI Synthetic cannabinoid Herbal blend LC–MS–MS GC–MS
Conflict of interest
There are no financial or other relations that could lead to a conflict of interest.
- 4.Uchiyama N, Shimokawa Y, Kawamura M, Kikura-Hanajiri R, Hakamatsuka T (2014) Chemical analysis of a benzofuran derivative, 2-(2-ethylaminopropyl) benzofuran (2-EAPB), eight synthetic cannabinoids, five cathinone derivatives, and five other designer drugs newly detected in illegal products. Forensic Toxicol 32:266–281CrossRefGoogle Scholar
- 7.Hasegawa K, Wurita A, Minakata K, Gonmori K, Nozawa H, Yamagishi I, Suzuki O, Watanabe K (2014) Identification and quantitation of a new cathinone designer drug PV9 in an “aroma liquid” product, antemortem whole blood and urine specimens, and a postmortem whole blood specimen in a fatal poisoning case. Forensic Toxicol 32:243–250CrossRefGoogle Scholar
- 9.Nakajima J, Takahashi M, Seto T, Kanai C, Suzuki J, Yoshida M, Hamano T (2011) Identification and quantitation of two benzoylindoles AM-694 and (4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone, and three cannabimimetic naphthoylindoles JWH-210, JWH-122, and JWH-019 as adulterants in illegal products obtained via the Internet. Forensic Toxicol 29:95–110CrossRefGoogle Scholar